ONTOLOGY REPORT - ANNOTATIONS


Term:endocrine system development
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Accession:GO:0035270 term browser browse the term
Definition:Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.


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endocrine system development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:1624291
adenohypophysis development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1624291
RGD:1600115
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:1601329
RGD:1624291
G Ghrhr growth hormone releasing hormone receptor JBrowse link 4 85,587,321 85,602,389 RGD:1624291
G Gsx1 GS homeobox 1 JBrowse link 12 9,605,873 9,607,168 RGD:1624291
RGD:1600115
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Pou1f1 POU class 1 homeobox 1 JBrowse link 11 2,645,659 2,662,581 RGD:1601440
G Prop1 PROP paired-like homeobox 1 JBrowse link 10 36,449,920 36,452,381 RGD:1624291
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:1624291
RGD:1600115
G Sox2 SRY box 2 JBrowse link 2 121,165,137 121,167,545 RGD:8661681
RGD:1624291
adenohypophysis morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Duox2 dual oxidase 2 JBrowse link 3 114,218,187 114,237,808 RGD:1624291
RGD:1600115
adrenal chromaffin cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:1624291
RGD:1600115
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:1624291
adrenal cortex formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 1 12,823,363 12,825,806 RGD:1624291
RGD:1600115
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
adrenal gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr2a activin A receptor type 2A JBrowse link 3 32,947,901 33,034,598 RGD:728125
G Acvr2b activin A receptor type 2B JBrowse link 8 128,087,308 128,126,776 RGD:728125
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
G Arid5b AT-rich interaction domain 5B JBrowse link 20 21,713,900 21,881,193 RGD:1624291
G Cdkn1c cyclin-dependent kinase inhibitor 1C JBrowse link 1 216,661,067 216,663,791 RGD:1624291
RGD:1600115
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 1 12,823,363 12,825,806 RGD:1624291
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:1624291
RGD:1600115
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:1624291
RGD:1600115
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1299585
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:4889133
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:4145970
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:7829725
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Fdx1 ferredoxin 1 JBrowse link 8 56,373,729 56,393,199 RGD:4145970
G Fstl3 follistatin like 3 JBrowse link 7 12,806,031 12,810,556 RGD:1302294
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:4889583
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:1624291
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1624291
RGD:1600115
G Ly6e lymphocyte antigen 6 family member E JBrowse link 7 116,355,426 116,359,862 RGD:1624291
G Mdk midkine JBrowse link 3 80,841,003 80,843,895 RGD:62414
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 JBrowse link X 54,734,385 54,738,513 RGD:1624291
RGD:1600115
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1624291
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 JBrowse link 3 22,998,900 23,020,441 RGD:1624291
RGD:1600115
G Pbx1 PBX homeobox 1 JBrowse link 13 86,390,741 86,671,460 RGD:1624291
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:1624291
RGD:1600115
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
G Pnmt phenylethanolamine-N-methyltransferase JBrowse link 10 86,340,893 86,342,501 RGD:5130728
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
RGD:1600115
G Smad2 SMAD family member 2 JBrowse link 18 72,550,107 72,612,078 RGD:728125
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:728125
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:728125
G Stra6 stimulated by retinoic acid 6 JBrowse link 8 62,925,364 62,944,438 RGD:1624291
RGD:1600115
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:2314319
G Thra_v1 thyroid hormone receptor alpha, variant 1 RGD:2314319
G Thra_v2 thyroid hormone receptor alpha, variant 2 RGD:2314319
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317174
G Wnt11 Wnt family member 11 JBrowse link 1 163,794,136 163,813,756 RGD:1624291
RGD:1600115
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:1600115
corticotropin hormone secreting cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
RGD:1600115
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
endocrine pancreas development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:2306957
RGD:13792537
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:2315710
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1582421
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
RGD:1600115
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
RGD:1600115
G Gip gastric inhibitory polypeptide JBrowse link 10 83,835,080 83,848,399 RGD:1624291
RGD:1600115
G Gipr gastric inhibitory polypeptide receptor JBrowse link 1 80,063,047 80,073,223 RGD:1624291
RGD:1600115
G Hnf1a HNF1 homeobox A JBrowse link 12 47,407,811 47,433,342 RGD:1600115
RGD:1624291
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
RGD:8554679
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
RGD:1600115
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:1624291
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:1624291
G Mnx1 motor neuron and pancreas homeobox 1 JBrowse link 4 2,376,350 2,381,308 RGD:1624291
RGD:13792537
G Myt1 myelin transcription factor 1 JBrowse link 3 177,281,365 177,341,550 RGD:1624291
G Neurod1 neuronal differentiation 1 JBrowse link 3 66,414,314 66,417,617 RGD:1600115
RGD:1624291
G Neurog3 neurogenin 3 JBrowse link 20 31,761,419 31,762,893 RGD:1600115
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:1624291
G Nkx6-2 NK6 homeobox 2 JBrowse link 1 211,922,389 211,923,929 RGD:1624291
RGD:1600115
G Onecut1 one cut homeobox 1 JBrowse link 8 81,765,779 81,799,894 RGD:1624291
RGD:1600115
G Onecut2 one cut homeobox 2 JBrowse link 18 59,830,375 59,882,490 RGD:1624291
G Pde3b phosphodiesterase 3B JBrowse link 1 183,892,841 184,078,071 RGD:1624291
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
RGD:13792537
G Rfx3 regulatory factor X3 JBrowse link 1 245,853,332 246,110,648 RGD:1624291
G Rfx6 regulatory factor X, 6 JBrowse link 20 32,709,282 32,764,040 RGD:1624291
RGD:13792537
G Sox4 SRY box 4 JBrowse link 17 37,615,022 37,619,728 RGD:1624291
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
hypophysis morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prop1 PROP paired-like homeobox 1 JBrowse link 10 36,449,920 36,452,381 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Mir7a1 microRNA 7a-1 JBrowse link 17 6,675,016 6,675,112 RGD:1624291
negative regulation of thyroid gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mir1 microRNA 1 JBrowse link 18 2,054,933 2,055,019 RGD:10059418
G Mir28 microRNA 28 JBrowse link 11 79,380,523 79,380,608 RGD:10059418
G Mir290 microRNA 290 JBrowse link 1 64,538,705 64,538,785 RGD:10059418
G Mir296 microRNA 296 JBrowse link 3 172,357,490 172,357,567 RGD:10059418
G Mir297 microRNA 297 JBrowse link 10 101,696,273 101,696,338 RGD:10059418
G Rap1gap Rap1 GTPase-activating protein JBrowse link 5 156,008,868 156,074,350 RGD:9835038
negative regulation of type B pancreatic cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cftr cystic fibrosis transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11567224
neurohypophysis development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Otp orthopedia homeobox JBrowse link 2 24,546,393 24,554,953 RGD:1624291
RGD:1600115
G Pou3f2 POU class 3 homeobox 2 JBrowse link 5 36,677,452 36,683,356 RGD:1624291
RGD:1600115
pancreatic A cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
RGD:8552352
pancreatic A cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:8552352
G Rfx6 regulatory factor X, 6 JBrowse link 20 32,709,282 32,764,040 RGD:1624291
RGD:13792537
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 4 145,580,869 145,587,835 RGD:1624291
RGD:1600115
pancreatic A cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Neurod1 neuronal differentiation 1 JBrowse link 3 66,414,314 66,417,617 RGD:1624291
RGD:1600115
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
RGD:1600115
pancreatic D cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rfx6 regulatory factor X, 6 JBrowse link 20 32,709,282 32,764,040 RGD:1624291
RGD:13792537
pancreatic epsilon cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rfx6 regulatory factor X, 6 JBrowse link 20 32,709,282 32,764,040 RGD:1624291
RGD:13792537
pancreatic PP cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Neurod1 neuronal differentiation 1 JBrowse link 3 66,414,314 66,417,617 RGD:1624291
RGD:1600115
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
RGD:1600115
parathyroid gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crkl CRK like proto-oncogene, adaptor protein JBrowse link 11 87,338,606 87,356,644 RGD:1624291
RGD:1600115
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
G Gcm2 glial cells missing transcription factor 2 JBrowse link 17 21,490,402 21,499,516 RGD:1624291
RGD:1600115
G Hoxa3 homeobox A3 JBrowse link 4 82,137,802 82,181,836 RGD:1624291
G LOC100911248 crk-like protein-like JBrowse link 11 87,778,338 87,815,049 RGD:1600115
G Pax1 paired box 1 JBrowse link 3 141,577,124 141,589,849 RGD:1624291
G Tbx1 T-box 1 JBrowse link 11 86,552,022 86,561,647 RGD:1624291
RGD:1600115
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1624291
pituitary gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:2325274
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:2306413
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 JBrowse link 1 127,302,920 127,337,828 RGD:2306413
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
RGD:1600115
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:2289637
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:1624291
RGD:1600115
G Ets1 ETS proto-oncogene 1, transcription factor JBrowse link 8 33,756,634 33,879,625 RGD:2313681
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:1624291
RGD:1600115
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
RGD:1600115
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
G Hesx1 HESX homeobox 1 JBrowse link 16 2,616,538 2,636,708 RGD:1624291
RGD:1600115
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
G Inhbb inhibin subunit beta B JBrowse link 13 35,436,532 35,442,222 RGD:2325274
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:1600115
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1624291
G Lhx3 LIM homeobox 3 JBrowse link 3 3,653,861 3,662,509 RGD:1624291
RGD:1600115
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:5132608
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1624291
RGD:1600115
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Pcsk1 proprotein convertase subtilisin/kexin type 1 JBrowse link 2 91,450,162 91,497,091 RGD:2308902
G Pitx1 paired-like homeodomain 1 JBrowse link 17 8,873,184 8,884,428 RGD:1624291
RGD:1600115
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:1624291
RGD:1600115
G Pou1f1 POU class 1 homeobox 1 JBrowse link 11 2,645,659 2,662,581 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
RGD:1600115
G Six3 SIX homeobox 3 JBrowse link 6 8,886,730 8,891,094 RGD:1624291
G Sox2 SRY box 2 JBrowse link 2 121,165,137 121,167,545 RGD:1624291
G Sox3 SRY-box 3 JBrowse link X 144,035,162 144,037,364 RGD:1624291
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:4892048
G Tbx19 T-box 19 JBrowse link 13 83,403,263 83,426,305 RGD:1624291
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1624291
positive regulation of type B pancreatic cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:1600115
G Rfx3 regulatory factor X3 JBrowse link 1 245,853,332 246,110,648 RGD:1624291
RGD:1600115
regulation of type B pancreatic cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arntl aryl hydrocarbon receptor nuclear translocator-like JBrowse link 1 178,039,002 178,137,469 RGD:1600115
RGD:1624291
G Clock clock circadian regulator JBrowse link 14 34,418,226 34,502,218 RGD:1600115
RGD:1624291
G Rheb Ras homolog, mTORC1 binding JBrowse link 4 6,827,429 6,873,384 RGD:1624291
RGD:1600115
somatotropin secreting cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ghrhr growth hormone releasing hormone receptor JBrowse link 4 85,587,321 85,602,389 RGD:1624291
RGD:1600115
G Pou1f1 POU class 1 homeobox 1 JBrowse link 11 2,645,659 2,662,581 RGD:1624291
RGD:1600115
somatotropin secreting cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pou1f1 POU class 1 homeobox 1 JBrowse link 11 2,645,659 2,662,581 RGD:1624291
G Prop1 PROP paired-like homeobox 1 JBrowse link 10 36,449,920 36,452,381 RGD:1624291
RGD:1600115
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115
thyroid gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:1624291
RGD:1600115
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:1624291
RGD:1600115
G Duox2 dual oxidase 2 JBrowse link 3 114,218,187 114,237,808 RGD:1624291
RGD:1600115
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
G Foxe1 forkhead box E1 JBrowse link 5 61,954,549 61,957,357 RGD:1624291
RGD:1600115
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Hoxa3 homeobox A3 JBrowse link 4 82,137,802 82,181,836 RGD:1624291
G Hoxa5 homeo box A5 RGD:1624291
G Hoxb3 homeo box B3 JBrowse link 10 84,170,629 84,196,823 RGD:1624291
RGD:1600115
G Hoxd3 homeo box D3 JBrowse link 3 61,650,569 61,670,285 RGD:1624291
RGD:1600115
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1624291
RGD:1600115
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:1624291
RGD:1600115
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
RGD:1600115
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
RGD:1600115
G Nkx2-1 NK2 homeobox 1 JBrowse link 6 77,418,096 77,423,383 RGD:1600115
RGD:1624291
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1600115
RGD:1624291
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Six1 SIX homeobox 1 JBrowse link 6 95,929,060 95,934,296 RGD:1624291
RGD:1600115
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1624291
RGD:1600115
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:1624291
RGD:1600115
G Tbx1 T-box 1 JBrowse link 11 86,552,022 86,561,647 RGD:1600115
RGD:1624291
G Tg thyroglobulin JBrowse link 7 107,467,260 107,652,897 RGD:1600115
RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:2302084
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:1624291
RGD:13792537
RGD:1600115
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:13792537
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
RGD:1600115
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115
type B pancreatic cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:1624291
RGD:1600115
G Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:1624291
RGD:1600115
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1600115
RGD:1624291
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:1600115
G Hnf4g hepatocyte nuclear factor 4, gamma JBrowse link 2 100,225,880 100,372,710 RGD:1600115
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:1624291
G Mir375 microRNA 375 JBrowse link 9 82,161,716 82,161,790 RGD:1624291
G Mir503 microRNA 503 JBrowse link X 158,148,476 158,148,546 RGD:1624291
G Mir541 microRNA 541 JBrowse link 6 133,892,655 133,892,744 RGD:1624291
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
RGD:1600115
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:2326025
G Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:1624291
RGD:1600115
G Sidt2 SID1 transmembrane family, member 2 JBrowse link 8 50,230,335 50,246,979 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
type B pancreatic cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:1624291
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:9589069
G Mir7a1 microRNA 7a-1 JBrowse link 17 6,675,016 6,675,112 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:8552355
RGD:1600115
RGD:1624291
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:8553608
RGD:13792537
RGD:1624291
G Rfx6 regulatory factor X, 6 JBrowse link 20 32,709,282 32,764,040 RGD:1624291
RGD:13792537
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 4 145,580,869 145,587,835 RGD:1624291
RGD:1600115
type B pancreatic cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkx2-2 NK2 homeobox 2 JBrowse link 3 141,408,460 141,419,083 RGD:1624291
RGD:1600115
type B pancreatic cell maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rfx3 regulatory factor X3 JBrowse link 1 245,853,332 246,110,648 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17895
    multicellular organismal process 8519
      multicellular organism development 5423
        system development 5002
          endocrine system development 170
            adrenal gland development + 43
            endocrine pancreas development + 52
            parathyroid gland development + 8
            pineal gland development 0
            pituitary gland development + 49
            ring gland development 0
            thyroid gland development + 34
Path 2
Term Annotations click to browse term
  biological_process 17895
    developmental process 6321
      anatomical structure development 5927
        multicellular organism development 5423
          system development 5002
            endocrine system development 170
              adrenal gland development + 43
              endocrine pancreas development + 52
              parathyroid gland development + 8
              pineal gland development 0
              pituitary gland development + 49
              ring gland development 0
              thyroid gland development + 34
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.