ONTOLOGY REPORT - ANNOTATIONS


Term:exocrine system development
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Accession:GO:0035272 term browser browse the term
Definition:Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.


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exocrine system development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab26 RAB26, member RAS oncogene family JBrowse link 10 13,894,271 13,898,578 RGD:8554411
RGD:1624291
branch elongation involved in salivary gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
branching involved in salivary gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
RGD:1600115
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:1624291
RGD:1600115
G Esrp1 epithelial splicing regulatory protein 1 JBrowse link 5 24,576,988 24,631,758 RGD:1624291
G Esrp2 epithelial splicing regulatory protein 2 JBrowse link 19 38,113,412 38,120,578 RGD:1624291
RGD:1600115
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgf7 fibroblast growth factor 7 JBrowse link 3 118,315,859 118,368,464 RGD:1624291
RGD:1600115
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1600115
RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
RGD:1600115
G Lama1 laminin subunit alpha 1 JBrowse link 9 115,916,907 116,042,123 RGD:1624291
RGD:1600115
G Lama5 laminin subunit alpha 5 JBrowse link 3 175,553,042 175,601,112 RGD:1624291
RGD:1600115
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Tgm2 transglutaminase 2 JBrowse link 3 154,597,165 154,627,257 RGD:1624291
RGD:1600115
cell differentiation involved in salivary gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcn2 chloride voltage-gated channel 2 JBrowse link 11 82,862,664 82,876,165 RGD:1624291
G Muc19 mucin 19, oligomeric JBrowse link 7 133,048,727 133,166,551 RGD:1624291
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
dichotomous subdivision of terminal units involved in salivary gland branching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
RGD:1600115
G Plxna1 plexin A1 JBrowse link 4 121,217,658 121,262,697 RGD:1624291
RGD:1600115
G Plxnd1 plexin D1 JBrowse link 4 147,854,309 147,894,170 RGD:1624291
RGD:1600115
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
RGD:1600115
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:1624291
RGD:1600115
epithelial cell differentiation involved in salivary gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnd1 catenin delta 1 JBrowse link 3 72,001,904 72,053,047 RGD:1624291
epithelial cell maturation involved in salivary gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
epithelial cell proliferation involved in salivary gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
RGD:1600115
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1624291
RGD:1600115
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
exocrine pancreas development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cela1 chymotrypsin like elastase 1 JBrowse link 7 142,305,337 142,318,621 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:1624291
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:1624291
RGD:1600115
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1624291
RGD:1600115
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
RGD:1600115
G Ptf1a pancreas associated transcription factor 1a JBrowse link 17 86,199,623 86,201,477 RGD:8554373
G Wls Wnt ligand secretion mediator JBrowse link 2 266,315,036 266,431,220 RGD:1624291
RGD:1600115
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
lacrimal gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
RGD:1600115
G Igsf3 immunoglobulin superfamily, member 3 JBrowse link 2 203,768,364 203,855,573 RGD:1624291
RGD:1600115
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Sox10 SRY box 10 JBrowse link 7 120,393,238 120,403,523 RGD:1624291
RGD:1600115
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
regulation of branching involved in salivary gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btbd7 BTB domain containing 7 JBrowse link 6 126,658,398 126,748,497 RGD:1624291
RGD:1600115
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:1624291
RGD:1600115
regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ntn4 netrin 4 JBrowse link 7 34,533,543 34,649,330 RGD:1624291
RGD:1600115
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fgf7 fibroblast growth factor 7 JBrowse link 3 118,315,859 118,368,464 RGD:1624291
RGD:1600115
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
RGD:1600115
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:1624291
RGD:1600115
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:1624291
salivary gland cavitation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:1624291
G Eda ectodysplasin-A JBrowse link X 69,730,123 70,222,693 RGD:1624291
RGD:1600115
G Edar ectodysplasin-A receptor JBrowse link 20 28,179,132 28,263,092 RGD:1624291
RGD:1600115
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Tgm2 transglutaminase 2 JBrowse link 3 154,597,165 154,627,257 RGD:1624291
RGD:1600115
salivary gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cst3 cystatin C JBrowse link 3 143,219,671 143,223,544 RGD:2306516
G Cyss cystatin S JBrowse link 3 144,427,430 144,431,768 RGD:2306516
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1624291
RGD:1600115
G Tfcp2l1 transcription factor CP2-like 1 JBrowse link 13 34,610,689 34,671,617 RGD:1624291
RGD:1600115
salivary gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
G Ctnnd1 catenin delta 1 JBrowse link 3 72,001,904 72,053,047 RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
RGD:1600115
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Polb DNA polymerase beta JBrowse link 16 74,237,001 74,260,272 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
RGD:1600115
G Twsg1 twisted gastrulation BMP signaling modulator 1 JBrowse link 9 113,699,151 113,732,601 RGD:1624291
RGD:1600115
submandibular salivary gland formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:5688282
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17895
    multicellular organismal process 8519
      multicellular organism development 5423
        system development 5002
          exocrine system development 60
            exocrine pancreas development 9
            lacrimal gland development 7
            salivary gland development + 47
Path 2
Term Annotations click to browse term
  biological_process 17895
    developmental process 6321
      anatomical structure development 5927
        multicellular organism development 5423
          system development 5002
            exocrine system development 60
              exocrine pancreas development 9
              lacrimal gland development 7
              salivary gland development + 47
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.