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ONTOLOGY REPORT - ANNOTATIONS


Term:thioester biosynthetic process
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Accession:GO:0035384 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
Synonyms:exact_synonym: thioester anabolism;   thioester biosynthesis;   thioester formation;   thioester synthesis


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acetyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
G Acly ATP citrate lyase JBrowse link 10 88,392,248 88,442,845 RGD:631761
RGD:13792537
RGD:1600115
RGD:1624291
G Acss1 acyl-CoA synthetase short-chain family member 1 JBrowse link 3 146,420,346 146,470,293 RGD:1624291
G Acss2 acyl-CoA synthetase short-chain family member 2 JBrowse link 3 151,032,925 151,075,856 RGD:1624291
G Mlycd malonyl-CoA decarboxylase JBrowse link 19 52,032,950 52,048,773 RGD:1600790
RGD:13792537
RGD:1624291
RGD:1600115
G Ppcs phosphopantothenoylcysteine synthetase JBrowse link 5 138,466,298 138,470,108 RGD:1624291
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acss1 acyl-CoA synthetase short-chain family member 1 JBrowse link 3 146,420,346 146,470,293 RGD:1600115
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlat dihydrolipoamide S-acetyltransferase JBrowse link 8 55,062,549 55,087,832 RGD:1599112
G Dld dihydrolipoamide dehydrogenase JBrowse link 6 50,597,677 50,618,694 RGD:1599112
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 37,329,779 37,343,410 RGD:1599112
RGD:13792537
RGD:1624291
RGD:1600115
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 JBrowse link 16 88,344,440 88,347,335 RGD:1600115
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 JBrowse link 2 246,736,449 246,737,997 RGD:1599112
RGD:13792537
G Pdhb pyruvate dehydrogenase E1 subunit beta JBrowse link 15 18,540,826 18,546,855 RGD:1599112
RGD:13792537
RGD:1624291
RGD:1600115
G Pdhx pyruvate dehydrogenase complex, component X JBrowse link 3 92,910,300 92,933,725 RGD:1600115
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:729541
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcdh glutaryl-CoA dehydrogenase JBrowse link 19 26,000,497 26,006,970 RGD:1598697
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:2312800
G Acsl4 acyl-CoA synthetase long-chain family member 4 JBrowse link X 113,596,247 113,660,024 RGD:2312800
G Acsl5 acyl-CoA synthetase long-chain family member 5 JBrowse link 1 276,240,703 276,290,012 RGD:2312800
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 10 39,654,771 39,717,592 RGD:2312800
G Elovl1 ELOVL fatty acid elongase 1 JBrowse link 5 137,255,868 137,260,486 RGD:1600115
G Elovl3 ELOVL fatty acid elongase 3 JBrowse link 1 265,883,353 265,887,181 RGD:1600115
G Elovl4 ELOVL fatty acid elongase 4 JBrowse link 8 91,310,690 91,338,625 RGD:1600115
G Elovl5 ELOVL fatty acid elongase 5 JBrowse link 8 85,220,941 85,287,449 RGD:1600115
G Elovl6 ELOVL fatty acid elongase 6 JBrowse link 2 234,187,490 234,296,124 RGD:1600115
G Elovl7 ELOVL fatty acid elongase 7 JBrowse link 2 40,373,211 40,386,643 RGD:1600115
G LOC102549542 elongation of very long chain fatty acids protein 6-like JBrowse link 2 234,375,172 234,486,639 RGD:1600115
malonyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:1600115
G Acacb acetyl-CoA carboxylase beta JBrowse link 12 48,127,149 48,238,969 RGD:1624291
mitochondrial acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpc1 mitochondrial pyruvate carrier 1 JBrowse link 1 53,026,608 53,038,229 RGD:1624291
G Mpc2 mitochondrial pyruvate carrier 2 JBrowse link 13 83,680,527 83,700,491 RGD:1624291
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 37,329,779 37,343,410 RGD:1624291
propionyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdk1 pyruvate dehydrogenase kinase 1 JBrowse link 3 58,530,870 58,561,494 RGD:1600115
RGD:1624291
G Pdk2 pyruvate dehydrogenase kinase 2 JBrowse link 10 82,838,270 82,852,758 RGD:1600115
RGD:1624291
G Pdk3 pyruvate dehydrogenase kinase 3 JBrowse link X 62,836,131 62,904,114 RGD:1624291
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:1600115
RGD:1624291
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      biosynthetic process 5989
        organic substance biosynthetic process 5875
          thioester biosynthetic process 34
            acyl-CoA biosynthetic process + 34
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      cellular metabolic process 10644
        sulfur compound metabolic process 294
          thioester metabolic process 88
            thioester biosynthetic process 34
              acyl-CoA biosynthetic process + 34
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.