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ONTOLOGY REPORT - ANNOTATIONS


Term:SNARE complex assembly
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Accession:GO:0035493 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


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SNARE complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snap25 synaptosome associated protein 25 IMP PMID:12680753
PMID:9671503
CAFA PMID:12680753, PMID:9671503 RGD:12793015, RGD:12793053 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400
JBrowse link
G Snca synuclein alpha ISO (PMID:20798282)
(MGI:MGI:5608839|PMID:25246573)
RGD PMID:20798282, PMID:25246573 MGI:MGI:5608839 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Stx1a syntaxin 1A IMP PMID:12680753
PMID:9671503
CAFA PMID:12680753, PMID:9671503 RGD:12793015, RGD:12793053 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Stx4 syntaxin 4 ISO
IEA
(MGI:MGI:5567905|PMID:21151919)
GO_REF:0000107
RGD
Ensembl
PMID:21151919 GO_REF:0000107, MGI:MGI:5567905 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO (PMID:23091057) RGD PMID:23091057 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Uvrag UV radiation resistance associated ISO
IBA
(MGI:MGI:5552992|PMID:24550300)
PMID:21873635
RGD PMID:24550300, PMID:21873635 MGI:MGI:5552992, RGD:13792537 NCBI chr 1:163,844,804...164,101,568
Ensembl chr 1:163,844,818...164,101,578
JBrowse link
G Vamp1 vesicle-associated membrane protein 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:157,726,941...157,733,644
Ensembl chr 4:157,726,941...157,733,643
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 IMP
IBA
PMID:12680753
PMID:21873635
PMID:9671503
CAFA
GO_Central
PMID:12680753, PMID:21873635, PMID:9671503 RGD:12793015, RGD:13792537, RGD:12793053 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 ISO
IBA
(MGI:MGI:5567905|PMID:21151919)
PMID:21873635
RGD PMID:21151919, PMID:21873635 MGI:MGI:5567905, RGD:13792537 NCBI chr 5:168,126,157...168,136,628
Ensembl chr 5:168,126,157...168,136,666
JBrowse link
G Vamp4 vesicle-associated membrane protein 4 ISO
IBA
(PMID:21151919)
PMID:21873635
RGD PMID:21151919, PMID:21873635 RGD:13792537 NCBI chr13:80,460,699...80,483,597
Ensembl chr13:80,460,694...80,483,600
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 ISO (MGI:MGI:5567905|PMID:21151919) RGD PMID:21151919 MGI:MGI:5567905 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 ISO
IBA
(MGI:MGI:5567905|PMID:21151919)
PMID:21873635
RGD PMID:21151919, PMID:21873635 MGI:MGI:5567905, RGD:13792537 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755
JBrowse link
negative regulation of SNARE complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd27 ankyrin repeat domain 27 ISO (PMID:24856514) RGD PMID:24856514 NCBI chr 1:91,857,048...91,958,763
Ensembl chr 1:91,857,057...91,958,763
JBrowse link
G Prrt2 proline-rich transmembrane protein 2 ISS
ISO
GO_REF:0000024
(MGI:MGI:6114881|PMID:29056747)
UniProt
RGD
PMID:29056747 GO_REF:0000024, MGI:MGI:6114881 NCBI chr 1:198,451,042...198,454,998
Ensembl chr 1:198,451,324...198,454,914
JBrowse link
G Stxbp1 syntaxin binding protein 1 TAS PMID:12093152 ParkinsonsUK-UCL PMID:12093152 RGD:730238 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Trim9 tripartite motif-containing 9 IDA RGD PMID:11524423 RGD:631246 NCBI chr 6:92,660,026...92,760,036
Ensembl chr 6:92,660,505...92,760,018
JBrowse link
positive regulation of SNARE complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cltrn collectrin, amino acid transport regulator ISO
IBA
(PMID:16330323)
PMID:21873635
RGD PMID:16330323, PMID:21873635 RGD:13792537 NCBI chr  X:32,118,082...32,153,687
Ensembl chr  X:32,118,054...32,153,794
JBrowse link
G Snca synuclein alpha ISO (PMID:20798282) RGD PMID:20798282 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
regulation of SNARE complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Septin8 septin 8 IDA PMID:19196426 UniProt PMID:19196426 RGD:13702278 NCBI chr10:38,877,422...38,906,480
Ensembl chr10:38,877,422...38,906,482
JBrowse link
G Stxbp6 syntaxin binding protein 6 ISO
ISS
(PMID:12145319)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:12145319 GO_REF:0000024 NCBI chr 6:65,086,483...65,319,527
Ensembl chr 6:65,089,318...65,319,527
JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:48,677,492...48,692,295
Ensembl chr 8:48,677,492...48,692,295
JBrowse link
G Vps16 VPS16 core subunit of CORVET and HOPS complexes IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:122,947,887...122,969,543
Ensembl chr 3:122,947,913...122,969,541
JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:111,097,352...111,108,206
Ensembl chr 3:111,097,326...111,108,295
JBrowse link
G Vps41 VPS41 subunit of HOPS complex IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr17:48,643,754...48,810,633
Ensembl chr17:48,648,879...48,810,991
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      vesicle-mediated transport 1652
        vesicle fusion 106
          SNARE complex assembly 22
            negative regulation of SNARE complex assembly 4
            positive regulation of SNARE complex assembly 2
            regulation of SNARE complex assembly + 12
Path 2
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular component organization or biogenesis 6766
        cellular component organization 6510
          organelle organization 4073
            organelle fusion 154
              organelle membrane fusion 111
                vesicle fusion 106
                  SNARE complex assembly 22
                    negative regulation of SNARE complex assembly 4
                    positive regulation of SNARE complex assembly 2
                    regulation of SNARE complex assembly + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.