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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H2B conserved C-terminal lysine deubiquitination
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Accession:GO:0035616 term browser browse the term
Definition:A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
Synonyms:narrow_synonym: budding yeast H2B K123 deubiquitination;   fission yeast H2B K119 deubiquitination;   mammalian H2B K120 deubiquitination


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histone H2B conserved C-terminal lysine deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPOP elongin BC and polycomb repressive complex 2 associated protein ISO (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chr17:18,599,046...18,602,293 JBrowse link
G USP15 ubiquitin specific peptidase 15 ISO (PMID:24526689) UniProtKB PMID:24526689 NCBI chr12:26,533,441...26,682,964
Ensembl chr12:26,808,337...26,954,099
JBrowse link
G USP49 ubiquitin specific peptidase 49 ISO (PMID:23824326) UniProtKB PMID:23824326 NCBI chr 6:41,375,083...41,479,143
Ensembl chr 6:42,683,149...42,695,707
JBrowse link
G USP7 ubiquitin specific peptidase 7 ISO (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chr16:7,825,332...7,895,095
Ensembl chr16:9,065,858...9,106,146
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 12524
    metabolic process 7962
      organic substance metabolic process 7650
        macromolecule metabolic process 6615
          macromolecule modification 3100
            covalent chromatin modification 417
              histone modification 403
                histone deubiquitination 23
                  histone H2B conserved C-terminal lysine deubiquitination 4
Path 2
Term Annotations click to browse term
  biological_process 12524
    metabolic process 7962
      organic substance metabolic process 7650
        organonitrogen compound metabolic process 4630
          protein metabolic process 3992
            protein modification process 2964
              cellular protein modification process 2964
                protein modification by small protein conjugation or removal 663
                  protein modification by small protein removal 111
                    protein deubiquitination 97
                      histone deubiquitination 23
                        histone H2B conserved C-terminal lysine deubiquitination 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.