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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H2B conserved C-terminal lysine deubiquitination
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Accession:GO:0035616 term browser browse the term
Definition:A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
Synonyms:narrow_synonym: budding yeast H2B K123 deubiquitination;   fission yeast H2B K119 deubiquitination;   mammalian H2B K120 deubiquitination


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histone H2B conserved C-terminal lysine deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Usp15 ubiquitin specific peptidase 15 ISO (PMID:24526689) UniProtKB PMID:24526689 NCBI chrNW_004955458:9,440,645...9,533,653 JBrowse link
G Usp49 ubiquitin specific peptidase 49 ISO (PMID:23824326) UniProtKB PMID:23824326 NCBI chrNW_004955437:8,187,118...8,237,910 JBrowse link
G Usp7 ubiquitin specific peptidase 7 ISO (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chrNW_004955442:9,316,022...9,355,751 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11857
    metabolic process 7593
      organic substance metabolic process 7299
        macromolecule metabolic process 6337
          macromolecule modification 2991
            covalent chromatin modification 400
              histone modification 387
                histone deubiquitination 21
                  histone H2B conserved C-terminal lysine deubiquitination 3
Path 2
Term Annotations click to browse term
  biological_process 11857
    metabolic process 7593
      organic substance metabolic process 7299
        organonitrogen compound metabolic process 4435
          protein metabolic process 3840
            protein modification process 2865
              cellular protein modification process 2865
                protein modification by small protein conjugation or removal 646
                  protein modification by small protein removal 105
                    protein deubiquitination 91
                      histone deubiquitination 21
                        histone H2B conserved C-terminal lysine deubiquitination 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.