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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H2B conserved C-terminal lysine deubiquitination
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Accession:GO:0035616 term browser browse the term
Definition:A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
Synonyms:narrow_synonym: budding yeast H2B K123 deubiquitination;   fission yeast H2B K119 deubiquitination;   mammalian H2B K120 deubiquitination


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histone H2B conserved C-terminal lysine deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPOP elongin BC and polycomb repressive complex 2 associated protein IEA Ensembl GO_REF:0000107 NCBI chr 9:23,549,088...23,552,433
Ensembl chr 9:23,549,615...23,550,754
JBrowse link
G USP15 ubiquitin specific peptidase 15 IEA Ensembl GO_REF:0000107 NCBI chr10:5,510,759...5,634,954
Ensembl chr10:5,510,022...5,634,202
JBrowse link
G USP49 ubiquitin specific peptidase 49 IEA Ensembl GO_REF:0000107 NCBI chr12:10,474,873...10,556,900
Ensembl chr12:10,479,733...10,577,918
JBrowse link
G USP7 ubiquitin specific peptidase 7 ISO (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chr 6:33,277,328...33,315,601
Ensembl chr 6:33,277,444...33,314,491
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 16162
    metabolic process 10639
      organic substance metabolic process 10116
        macromolecule metabolic process 8792
          macromolecule modification 3923
            covalent chromatin modification 487
              histone modification 473
                histone deubiquitination 25
                  histone H2B conserved C-terminal lysine deubiquitination 4
Path 2
Term Annotations click to browse term
  biological_process 16162
    metabolic process 10639
      organic substance metabolic process 10116
        organonitrogen compound metabolic process 6195
          protein metabolic process 5376
            protein modification process 3736
              cellular protein modification process 3736
                protein modification by small protein conjugation or removal 900
                  protein modification by small protein removal 143
                    protein deubiquitination 125
                      histone deubiquitination 25
                        histone H2B conserved C-terminal lysine deubiquitination 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.