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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H2B conserved C-terminal lysine deubiquitination
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Accession:GO:0035616 term browser browse the term
Definition:A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
Synonyms:narrow_synonym: budding yeast H2B K123 deubiquitination;   fission yeast H2B K119 deubiquitination;   mammalian H2B K120 deubiquitination


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histone H2B conserved C-terminal lysine deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epop elongin BC and polycomb repressive complex 2 associated protein IMP (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chr11:97,627,387...97,629,716
Ensembl chr11:97,627,389...97,629,702
JBrowse link
G Usp15 ubiquitin specific peptidase 15 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr10:123,105,006...123,197,281
Ensembl chr10:123,105,006...123,196,995
JBrowse link
G Usp49 ubiquitin specific peptidase 49 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr17:47,630,690...47,686,739
Ensembl chr17:47,630,690...47,686,738
JBrowse link
G Usp7 ubiquitin specific peptidase 7 IMP (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chr16:8,688,722...8,757,067
Ensembl chr16:8,689,595...8,792,308
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23360
    metabolic process 11269
      organic substance metabolic process 10739
        macromolecule metabolic process 9262
          macromolecule modification 3848
            covalent chromatin modification 479
              histone modification 465
                histone deubiquitination 24
                  histone H2B conserved C-terminal lysine deubiquitination 4
Path 2
Term Annotations click to browse term
  biological_process 23360
    metabolic process 11269
      organic substance metabolic process 10739
        organonitrogen compound metabolic process 6248
          protein metabolic process 5404
            protein modification process 3656
              cellular protein modification process 3656
                protein modification by small protein conjugation or removal 830
                  protein modification by small protein removal 140
                    protein deubiquitination 119
                      histone deubiquitination 24
                        histone H2B conserved C-terminal lysine deubiquitination 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.