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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H2B conserved C-terminal lysine deubiquitination
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Accession:GO:0035616 term browser browse the term
Definition:A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
Synonyms:narrow_synonym: budding yeast H2B K123 deubiquitination;   fission yeast H2B K119 deubiquitination;   mammalian H2B K120 deubiquitination


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histone H2B conserved C-terminal lysine deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPOP elongin BC and polycomb repressive complex 2 associated protein IEA Ensembl GO_REF:0000107 NCBI chr12:23,435,388...23,438,235
Ensembl chr12:23,435,402...23,436,541
JBrowse link
G USP15 ubiquitin specific peptidase 15 IEA Ensembl GO_REF:0000107 NCBI chr 5:26,964,380...27,082,549
Ensembl chr 5:26,964,510...27,097,458
JBrowse link
G USP49 ubiquitin specific peptidase 49 IEA Ensembl GO_REF:0000107 NCBI chr 7:36,978,291...37,054,027
Ensembl chr 7:36,981,383...37,030,151
JBrowse link
G USP7 ubiquitin specific peptidase 7 ISO (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chr 3:33,754,357...33,810,480
Ensembl chr 3:33,775,829...33,810,466
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 16524
    metabolic process 10565
      organic substance metabolic process 10015
        macromolecule metabolic process 8711
          macromolecule modification 3889
            covalent chromatin modification 480
              histone modification 466
                histone deubiquitination 23
                  histone H2B conserved C-terminal lysine deubiquitination 4
Path 2
Term Annotations click to browse term
  biological_process 16524
    metabolic process 10565
      organic substance metabolic process 10015
        organonitrogen compound metabolic process 6072
          protein metabolic process 5289
            protein modification process 3704
              cellular protein modification process 3704
                protein modification by small protein conjugation or removal 882
                  protein modification by small protein removal 134
                    protein deubiquitination 117
                      histone deubiquitination 23
                        histone H2B conserved C-terminal lysine deubiquitination 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.