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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H2B conserved C-terminal lysine deubiquitination
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Accession:GO:0035616 term browser browse the term
Definition:A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
Synonyms:narrow_synonym: budding yeast H2B K123 deubiquitination;   fission yeast H2B K119 deubiquitination;   mammalian H2B K120 deubiquitination


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histone H2B conserved C-terminal lysine deubiquitination term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epop elongin BC and polycomb repressive complex 2 associated protein ISO (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chrNW_004936490:14,086,278...14,088,746 JBrowse link
G Usp15 ubiquitin specific peptidase 15 ISO (PMID:24526689) UniProtKB PMID:24526689 NCBI chrNW_004936545:978,318...1,094,729 JBrowse link
G Usp49 ubiquitin specific peptidase 49 ISO (PMID:23824326) UniProtKB PMID:23824326 NCBI chrNW_004936476:17,946,875...18,002,081 JBrowse link
G Usp7 ubiquitin specific peptidase 7 ISO (MGI:MGI:5822935|PMID:27863226) UniProtKB PMID:27863226 MGI:MGI:5822935 NCBI chrNW_004936530:7,693,681...7,724,215 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      organic substance metabolic process 7353
        macromolecule metabolic process 6381
          macromolecule modification 3026
            covalent chromatin modification 409
              histone modification 396
                histone deubiquitination 23
                  histone H2B conserved C-terminal lysine deubiquitination 4
Path 2
Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      organic substance metabolic process 7353
        organonitrogen compound metabolic process 4476
          protein metabolic process 3874
            protein modification process 2900
              cellular protein modification process 2900
                protein modification by small protein conjugation or removal 654
                  protein modification by small protein removal 109
                    protein deubiquitination 95
                      histone deubiquitination 23
                        histone H2B conserved C-terminal lysine deubiquitination 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.