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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


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regulation of lysosomal lumen pH term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC681325 hypothetical protein LOC681325 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:80,359,555...80,363,168
Ensembl chr  X:80,359,555...80,363,168
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:22012985) RGD PMID:22012985 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 ISO
IBA
(PMID:31001245)
PMID:21873635
RGD PMID:31001245, PMID:21873635 RGD:13792537 NCBI chr  X:54,390,733...54,409,466
Ensembl chr  X:54,390,733...54,409,466
JBrowse link
G Tmem165 transmembrane protein 165 ISO
ISS
(PMID:23569283)
GO_REF:0000024
RGD
UniProt
PMID:23569283 GO_REF:0000024 NCBI chr14:34,503,037...34,528,262
Ensembl chr14:34,503,038...34,528,262
JBrowse link
G Tmem175 transmembrane protein 175 ISO
ISS
(MGI:MGI:5693670|PMID:26317472)
GO_REF:0000024
RGD
UniProt
PMID:26317472 GO_REF:0000024, MGI:MGI:5693670 NCBI chr14:2,083,745...2,100,006
Ensembl chr14:2,083,712...2,100,005
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes ISO
ISS
(PMID:28013294)
GO_REF:0000024
RGD
UniProt
PMID:28013294 GO_REF:0000024 NCBI chr12:38,459,816...38,482,903
Ensembl chr12:38,459,832...38,484,512
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 ISO
ISS
(PMID:32276428)
GO_REF:0000024
RGD
UniProt
PMID:32276428 GO_REF:0000024 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Ccdc115 coiled-coil domain containing 115 ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:37,774,876...37,778,839
Ensembl chr 9:37,775,311...37,779,967
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
IBA
ISS
(PMID:11722572)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:11722572, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
G Cln5 CLN5, intracellular trafficking protein ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:93,634,815...93,644,146 JBrowse link
G Cln6 CLN6, transmembrane ER protein ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:67,733,215...67,748,170
Ensembl chr 8:67,733,215...67,748,172
JBrowse link
G Grn granulin precursor ISS
ISO
IEA
GO_REF:0000024
(PMID:28073925)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28073925 GO_REF:0000024, GO_REF:0000107 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 ISO
ISS
(PMID:11722572)
PMID:8895569
RGD PMID:11722572, PMID:8895569 RGD:8553248 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Snapin SNAP-associated protein ISO MGI:MGI:3608768 (MGI:MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:MGI:4879078 NCBI chr 2:189,878,159...189,880,743
Ensembl chr 2:189,878,168...189,880,743
JBrowse link
G Tmem199 transmembrane protein 199 ISO
ISS
(PMID:28296633)
GO_REF:0000024
RGD
UniProt
PMID:28296633 GO_REF:0000024 NCBI chr10:65,775,721...65,780,293
Ensembl chr10:65,775,715...65,780,349
JBrowse link
G Tmem9 transmembrane protein 9 ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:52,854,031...52,871,300
Ensembl chr13:52,854,031...52,871,297
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
ISS
(PMID:10924275)
GO_REF:0000024
RGD
UniProt
PMID:10924275 GO_REF:0000024 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular component organization or biogenesis 6766
        cellular component organization 6510
          organelle organization 4073
            vacuole organization 197
              lytic vacuole organization 77
                lysosome organization 77
                  regulation of lysosomal lumen pH 16
                    lysosomal lumen acidification 10
                    lysosomal lumen pH elevation 1
Path 2
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological quality 4284
        homeostatic process 2090
          chemical homeostasis 1328
            ion homeostasis 882
              cation homeostasis 801
                monovalent inorganic cation homeostasis 157
                  cellular monovalent inorganic cation homeostasis 106
                    regulation of cellular pH 82
                      regulation of intracellular pH 73
                        regulation of lysosomal lumen pH 16
                          lysosomal lumen acidification 10
                          lysosomal lumen pH elevation 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.