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ONTOLOGY REPORT - ANNOTATIONS


Term:CD4-positive, alpha-beta T cell costimulation
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Accession:GO:0035783 term browser browse the term
Definition:The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.


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CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
negative regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1624291
positive regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    immune system process 2798
      lymphocyte costimulation 34
        T cell costimulation 31
          CD4-positive, alpha-beta T cell costimulation 3
            negative regulation of CD4-positive, alpha-beta T cell costimulation 1
            positive regulation of CD4-positive, alpha-beta T cell costimulation 1
            regulation of CD4-positive, alpha-beta T cell costimulation + 2
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          regulation of cell activation 745
            regulation of leukocyte activation 699
              regulation of lymphocyte activation 578
                regulation of T cell activation 332
                  regulation of alpha-beta T cell activation 111
                    positive regulation of alpha-beta T cell activation 69
                      positive regulation of CD4-positive, alpha-beta T cell activation 36
                        CD4-positive, alpha-beta T cell costimulation 3
                          negative regulation of CD4-positive, alpha-beta T cell costimulation 1
                          positive regulation of CD4-positive, alpha-beta T cell costimulation 1
                          regulation of CD4-positive, alpha-beta T cell costimulation + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.