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ONTOLOGY REPORT - ANNOTATIONS


Term:homologous recombination
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Accession:GO:0035825 term browser browse the term
Definition:A DNA recombination process that results in the equal exchange of genetic material between the recombining DNA molecules.
Synonyms:exact_synonym: interchromosomal DNA recombination;   interstrand DNA recombination
 narrow_synonym: reciprocal DNA recombination
 related_synonym: chromosomal crossover
 xref: Wikipedia:Chromosomal_crossover


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homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac10 histone deacetylase 10 JBrowse link 7 130,102,335 130,109,036 RGD:1600115
RGD:1624291
chiasma assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brip1 BRCA1 interacting protein C-terminal helicase 1 JBrowse link 10 73,507,009 73,632,742 RGD:1624291
G Ccnb1ip1 cyclin B1 interacting protein 1 JBrowse link 15 27,720,220 27,736,528 RGD:1624291
G Rnf212 ring finger protein 212 JBrowse link 14 1,959,148 1,998,077 RGD:1624291
G Sycp1 synaptonemal complex protein 1 JBrowse link 2 205,274,766 205,426,869 RGD:1624291
RGD:1600115
G Sycp3 synaptonemal complex protein 3 JBrowse link 7 29,029,887 29,044,344 RGD:1624291
G Tex11 testis expressed 11 JBrowse link X 70,670,212 70,946,621 RGD:1624291
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
double-strand break repair involved in meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brip1 BRCA1 interacting protein C-terminal helicase 1 JBrowse link 10 73,507,009 73,632,742 RGD:1624291
RGD:13792537
G Fancd2 FA complementation group D2 JBrowse link 4 145,489,869 145,551,479 RGD:13792537
G Mcmdc2 minichromosome maintenance domain containing 2 JBrowse link 5 8,973,861 9,039,616 RGD:1624291
RGD:1600115
G Morc2b microrchidia 2B JBrowse link 7 15,479,754 15,483,834 RGD:1600115
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1600115
RGD:1624291
G Spo11 SPO11, initiator of meiotic double stranded breaks JBrowse link 3 170,991,573 171,008,226 RGD:1624291
meiotic DNA double-strand break processing involved in reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brip1 BRCA1 interacting protein C-terminal helicase 1 JBrowse link 10 73,507,009 73,632,742 RGD:1624291
G Six6os1 Six6 opposite strand transcript 1 JBrowse link 6 95,761,718 95,797,314 RGD:1624291
RGD:13792537
positive regulation of reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1624291
RGD:13792537
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
reciprocal meiotic recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnb1ip1 cyclin B1 interacting protein 1 JBrowse link 15 27,720,220 27,736,528 RGD:1624291
RGD:13792537
G Cep63 centrosomal protein 63 JBrowse link 8 111,063,988 111,116,014 RGD:1624291
G Chtf18 chromosome transmission fidelity factor 18 JBrowse link 10 15,090,762 15,098,825 RGD:1624291
G Cntd1 cyclin N-terminal domain containing 1 JBrowse link 10 89,199,988 89,210,369 RGD:1624291
G Dmc1 DNA meiotic recombinase 1 JBrowse link 7 120,796,217 120,840,524 RGD:13792537
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
G Mnd1 meiotic nuclear divisions 1 JBrowse link 2 183,073,029 183,140,768 RGD:13792537
G Msh3 mutS homolog 3 JBrowse link 2 21,790,048 21,931,791 RGD:13792537
G Msh4 mutS homolog 4 JBrowse link 2 260,057,708 260,108,897 RGD:13792537
G Msh5 mutS homolog 5 JBrowse link 20 5,020,690 5,037,125 RGD:13792537
G Psmc3ip PSMC3 interacting protein JBrowse link 10 89,002,109 89,006,075 RGD:1600115
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:68816
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:13792537
G Rad51c RAD51 paralog C JBrowse link 10 74,697,713 74,724,004 RGD:1624291
RGD:13792537
G Rad51d RAD51 paralog D JBrowse link 10 70,222,703 70,241,352 RGD:13792537
G Rad54b RAD54 homolog B JBrowse link 5 25,140,531 25,214,469 RGD:13792537
G RGD1563323 similar to hypothetical protein FLJ22531 JBrowse link 1 219,864,108 219,952,143 RGD:1624291
G Rnf212 ring finger protein 212 JBrowse link 14 1,959,148 1,998,077 RGD:1624291
G Spo11 SPO11, initiator of meiotic double stranded breaks JBrowse link 3 170,991,573 171,008,226 RGD:1624291
RGD:13792537
G Syce3 synaptonemal complex central element protein 3 JBrowse link 7 130,360,511 130,386,673 RGD:1624291
RGD:13792537
G Sycp1 synaptonemal complex protein 1 JBrowse link 2 205,274,766 205,426,869 RGD:1624291
RGD:1600115
G Tex11 testis expressed 11 JBrowse link X 70,670,212 70,946,621 RGD:1624291
RGD:13792537
G Tex19.1 testis expressed 19.1 JBrowse link 10 110,346,453 110,348,655 RGD:1600115
G Trip13 thyroid hormone receptor interactor 13 JBrowse link 1 31,967,980 32,012,923 RGD:1600115
RGD:13792537
RGD:1624291
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 JBrowse link 9 16,003,058 16,080,152 RGD:1624291
resolution of meiotic recombination intermediates term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07030926.1 RGD:13792537
G AABR07048387.1 RGD:1600115
G AC117889.1 RGD:13792537
G Cenps centromere protein S JBrowse link 5 165,946,106 165,955,723 RGD:1624291
G Cenpx centromere protein X JBrowse link 10 109,890,904 109,893,804 RGD:1624291
G Eme1 essential meiotic structure-specific endonuclease 1 JBrowse link 10 82,366,820 82,375,510 RGD:13792537
G Eme2 essential meiotic structure-specific endonuclease subunit 2 JBrowse link 10 14,253,552 14,257,017 RGD:13792537
G Fancm FA complementation group M JBrowse link 6 86,823,195 86,877,067 RGD:1624291
G Hfm1 helicase for meiosis 1 JBrowse link 14 3,879,172 3,961,139 RGD:1624291
RGD:13792537
G Meiob meiosis specific with OB-fold JBrowse link 10 14,174,645 14,206,026 RGD:1600115
RGD:13792537
RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh4 mutS homolog 4 JBrowse link 2 260,057,708 260,108,897 RGD:13792537
G Mus81 MUS81 structure-specific endonuclease subunit JBrowse link 1 220,862,474 220,867,973 RGD:13792537
G Rmi1 RecQ mediated genome instability 1 JBrowse link 17 6,658,285 6,665,618 RGD:13792537
G Shoc1 shortage in chiasmata 1 JBrowse link 5 76,190,486 76,298,723 RGD:1624291
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:13792537
G Tex11 testis expressed 11 JBrowse link X 70,670,212 70,946,621 RGD:1624291
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    cellular process 18179
      cellular metabolic process 10644
        cellular macromolecule metabolic process 8181
          DNA metabolic process 885
            DNA recombination 307
              homologous recombination 49
                reciprocal meiotic recombination + 48
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      cellular metabolic process 10644
        cellular nitrogen compound metabolic process 6382
          nucleobase-containing compound metabolic process 5278
            nucleic acid metabolic process 4788
              DNA metabolic process 885
                DNA recombination 307
                  homologous recombination 49
                    reciprocal meiotic recombination + 48
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.