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ONTOLOGY REPORT - ANNOTATIONS


Term:epithelial cell differentiation involved in kidney development
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Accession:GO:0035850 term browser browse the term
Definition:The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state.


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glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:1624291
RGD:1600115
G Foxc2 forkhead box C2 JBrowse link 19 53,044,379 53,047,081 RGD:1624291
G Gpr4 G protein-coupled receptor 4 JBrowse link 1 80,125,639 80,136,786 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
glomerular parietal epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
glomerular parietal epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
RGD:1600115
G Prom1 prominin 1 JBrowse link 14 71,532,321 71,637,400 RGD:1624291
glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ampd2 adenosine monophosphate deaminase 2 JBrowse link 2 210,861,624 210,874,348 RGD:1624291
G Asxl1 ASXL transcriptional regulator 1 JBrowse link 3 148,832,231 148,902,356 RGD:1600115
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:1600115
RGD:1624291
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 4 10,995,241 12,472,423 RGD:8553727
G Myo1e myosin IE JBrowse link 8 76,644,715 76,840,240 RGD:1624291
RGD:1600115
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1624291
RGD:1600115
G Nphs1 NPHS1 adhesion molecule, nephrin JBrowse link 1 88,922,346 88,950,560 RGD:1600115
RGD:1624291
G Podxl podocalyxin-like JBrowse link 4 58,829,049 58,893,353 RGD:8553727
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
glomerular visceral epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Basp1 brain abundant, membrane attached signal protein 1 JBrowse link 2 77,586,424 77,632,626 RGD:1624291
RGD:1600115
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
RGD:1600115
G Foxc2 forkhead box C2 JBrowse link 19 53,044,379 53,047,081 RGD:1624291
G Klf15 Kruppel-like factor 15 JBrowse link 4 122,364,688 122,377,690 RGD:1624291
G Prom1 prominin 1 JBrowse link 14 71,532,321 71,637,400 RGD:1624291
G Ptpro protein tyrosine phosphatase, receptor type, O JBrowse link 4 171,250,766 171,461,571 RGD:1624291
RGD:1600115
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:1624291
RGD:13792537
RGD:1600115
mesenchymal to epithelial transition involved in metanephric renal vesicle formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1600115
RGD:1624291
mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:8656002
RGD:1624291
RGD:1600115
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
G Six2 SIX homeobox 2 JBrowse link 6 8,952,572 8,955,893 RGD:1624291
metanephric glomerular mesangial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
RGD:1600115
metanephric glomerular mesangial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:1624291
metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lamb2 laminin subunit beta 2 JBrowse link 8 117,268,335 117,280,517 RGD:1624291
RGD:1600115
G Nphs2 NPHS2 stomatin family member, podocin JBrowse link 13 73,929,136 73,941,522 RGD:1624291
negative regulation of epithelial cell differentiation involved in kidney development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1600115
RGD:1624291
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:8554075
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
negative regulation of nephron tubule epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Osr1 odd-skipped related transcription factor 1 JBrowse link 6 35,314,431 35,321,458 RGD:1624291
RGD:1600115
nephron tubule epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Mtss1 MTSS I-BAR domain containing 1 JBrowse link 7 98,820,799 98,960,878 RGD:1624291
RGD:1600115
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1600115
RGD:1624291
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
positive regulation of metanephric glomerular visceral epithelial cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:1624291
RGD:1600115
positive regulation of nephron tubule epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
RGD:1600115
G Lhx1 LIM homeobox 1 JBrowse link 10 71,843,991 71,849,293 RGD:1624291
RGD:1600115
G Prom1 prominin 1 JBrowse link 14 71,532,321 71,637,400 RGD:1624291
regulation of epithelial cell differentiation involved in kidney development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prkx protein kinase, X-linked JBrowse link X 45,080,963 45,125,095 RGD:1624291
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt9b Wnt family member 9B JBrowse link 10 91,785,892 91,808,061 RGD:1624291
regulation of metanephric nephron tubule epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fat4 FAT atypical cadherin 4 JBrowse link 2 125,751,818 125,879,398 RGD:1624291
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1624291
RGD:1600115
G Pax8 paired box 8 JBrowse link 3 1,527,316 1,586,019 RGD:1624291
RGD:1600115
G Wwtr1 WW domain containing transcription regulator 1 JBrowse link 2 147,577,149 147,693,033 RGD:1624291
G Yap1 Yes1 associated transcriptional regulator JBrowse link 8 6,133,014 6,204,240 RGD:1624291
regulation of nephron tubule epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1600115
RGD:1624291
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cellular process 17240
      cellular developmental process 4415
        cell differentiation 4195
          epithelial cell differentiation 668
            epithelial cell differentiation involved in kidney development 46
              glomerular epithelial cell differentiation + 20
              glomerular mesangial cell differentiation + 6
              mesenchymal to epithelial transition involved in mesonephros morphogenesis + 0
              mesenchymal to epithelial transition involved in metanephros morphogenesis + 12
              mesenchymal to epithelial transition involved in renal vesicle formation + 1
              negative regulation of epithelial cell differentiation involved in kidney development + 5
              nephron tubule epithelial cell differentiation + 14
              positive regulation of epithelial cell differentiation involved in kidney development + 8
              regulation of epithelial cell differentiation involved in kidney development + 19
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            urogenital system development 405
              renal system development 356
                kidney development 341
                  cell differentiation involved in kidney development 56
                    epithelial cell differentiation involved in kidney development 46
                      glomerular epithelial cell differentiation + 20
                      glomerular mesangial cell differentiation + 6
                      mesenchymal to epithelial transition involved in mesonephros morphogenesis + 0
                      mesenchymal to epithelial transition involved in metanephros morphogenesis + 12
                      mesenchymal to epithelial transition involved in renal vesicle formation + 1
                      negative regulation of epithelial cell differentiation involved in kidney development + 5
                      nephron tubule epithelial cell differentiation + 14
                      positive regulation of epithelial cell differentiation involved in kidney development + 8
                      regulation of epithelial cell differentiation involved in kidney development + 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.