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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular smooth muscle cell differentiation
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Accession:GO:0035886 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.
Synonyms:exact_synonym: VSMC differentiation;   vascular associated smooth muscle cell differentiation


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vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epc1 enhancer of polycomb homolog 1 JBrowse link 17 57,303,968 57,394,975 RGD:9587795
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:1624291
aortic smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 JBrowse link 1 244,615,811 244,783,736 RGD:1624291
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:1624291
cardiac vascular smooth muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1600115
RGD:1624291
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
G Mir143 microRNA 143 JBrowse link 18 56,971,273 56,971,377 RGD:1624291
G Mir145 microRNA 145 JBrowse link 18 56,969,907 56,969,994 RGD:1624291
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:1624291
negative regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Klf5 Kruppel-like factor 5 JBrowse link 15 83,703,796 83,722,921 RGD:13210556
negative regulation of vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfatc1 nuclear factor of activated T-cells 1 JBrowse link 18 77,203,517 77,322,690 RGD:1624291
G Nfatc2 nuclear factor of activated T-cells 2 JBrowse link 3 165,241,750 165,374,644 RGD:1624291
G Nfatc3 nuclear factor of activated T-cells 3 JBrowse link 19 38,039,542 38,114,003 RGD:1624291
G Pdcd4 programmed cell death 4 JBrowse link 1 274,616,625 274,648,204 RGD:1624291
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
RGD:1600115
negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:1600115
RGD:1624291
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:13601993
positive regulation of aortic smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cth cystathionine gamma-lyase JBrowse link 2 264,266,959 264,293,040 RGD:1624291
positive regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:1624291
RGD:1600115
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:8554320
positive regulation of vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:1624291
positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1624291
regulation of aortic smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sdc4 syndecan 4 JBrowse link 3 160,872,503 160,891,190 RGD:11079193
vascular smooth muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1624291
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:1624291
RGD:1600115
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Ramp2 receptor activity modifying protein 2 JBrowse link 10 89,166,170 89,168,962 RGD:1624291
RGD:1600115
G Sgcb sarcoglycan, beta JBrowse link 14 37,113,194 37,128,623 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    multicellular organismal process 8814
      multicellular organism development 5579
        system development 5100
          vasculature development 755
            vascular smooth muscle cell differentiation 32
              aortic smooth muscle cell differentiation + 4
              cardiac vascular smooth muscle cell differentiation + 11
              negative regulation of vascular smooth muscle cell differentiation + 8
              positive regulation of vascular smooth muscle cell differentiation + 6
              regulation of vascular smooth muscle cell differentiation + 15
              vascular smooth muscle cell development + 9
              vascular smooth muscle cell differentiation involved in phenotypic switching + 3
              vascular smooth muscle cell fate commitment + 0
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            circulatory system development 1201
              cardiovascular system development 769
                vasculature development 755
                  vascular smooth muscle cell differentiation 32
                    aortic smooth muscle cell differentiation + 4
                    cardiac vascular smooth muscle cell differentiation + 11
                    negative regulation of vascular smooth muscle cell differentiation + 8
                    positive regulation of vascular smooth muscle cell differentiation + 6
                    regulation of vascular smooth muscle cell differentiation + 15
                    vascular smooth muscle cell development + 9
                    vascular smooth muscle cell differentiation involved in phenotypic switching + 3
                    vascular smooth muscle cell fate commitment + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.