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ONTOLOGY REPORT - ANNOTATIONS


Term:aorta development
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Accession:GO:0035904 term browser browse the term
Definition:The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.


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aorta development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 2:34,374,142...34,589,676
Ensembl chr 2:34,374,158...34,586,755
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 ISO MGI:MGI:2176467|MGI:MGI:4433295 (MGI:MGI:5694290|PMID:26102480) RGD PMID:26102480 MGI:MGI:5694290 NCBI chr 5:21,769,087...21,952,036
Ensembl chr 5:21,830,882...21,950,696
JBrowse link
G Cntrl centriolin ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 3:14,299,441...14,371,681
Ensembl chr 3:14,299,479...14,371,681
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Dctn5 dynactin subunit 5 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 1:192,088,709...192,105,421
Ensembl chr 1:192,088,672...192,105,429
JBrowse link
G Dnm2 dynamin 2 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Eln elastin IEP RGD PMID:18803461 RGD:7394730 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Fuz fuzzy planar cell polarity protein ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 1:100,891,832...100,896,811
Ensembl chr 1:100,891,866...100,896,807
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 6:72,509,658...72,596,285
Ensembl chr 6:72,510,255...72,596,446
JBrowse link
G Kif7 kinesin family member 7 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 1:141,434,183...141,452,592
Ensembl chr 1:141,434,625...141,451,075
JBrowse link
G Lep leptin ISO MGI:MGI:1856424 (MGI:MGI:5616293|PMID:23413430) RGD PMID:23413430 MGI:MGI:5616293 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lox lysyl oxidase ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Loxl1 lysyl oxidase-like 1 IEP RGD PMID:18803461 RGD:7394730 NCBI chr 8:63,067,757...63,092,124
Ensembl chr 8:63,067,300...63,092,009
JBrowse link
G Lrp2 LDL receptor related protein 2 ISO
IEA
(MGI:MGI:5644076|PMID:25807483)
GO_REF:0000107
RGD
Ensembl
PMID:25807483 GO_REF:0000107, MGI:MGI:5644076 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 ISO
IEA
(MGI:MGI:5644076|PMID:25807483)
GO_REF:0000107
RGD
Ensembl
PMID:25807483 GO_REF:0000107, MGI:MGI:5644076 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
JBrowse link
G Myh10 myosin heavy chain 10 ISO
IEA
(MGI:MGI:5644076|PMID:25807483)
GO_REF:0000107
RGD
Ensembl
PMID:25807483 GO_REF:0000107, MGI:MGI:5644076 NCBI chr10:55,274,910...55,406,738
Ensembl chr10:55,275,411...55,406,732
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr18:55,951,497...56,014,107
Ensembl chr18:55,955,389...55,992,885
JBrowse link
G Pde2a phosphodiesterase 2A ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 1:166,534,643...166,626,158
Ensembl chr 1:166,534,643...166,626,158
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO (PMID:11891195) RGD PMID:11891195 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Plxnd1 plexin D1 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 4:147,854,309...147,894,170
Ensembl chr 4:147,854,309...147,893,992
JBrowse link
G Prdm1 PR/SET domain 1 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prickle1 prickle planar cell polarity protein 1 ISO
IEA
(MGI:MGI:5644076|PMID:25807483)
GO_REF:0000107
RGD
Ensembl
PMID:25807483 GO_REF:0000107, MGI:MGI:5644076 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO UniProtKB:Q7TPD3 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 ISO UniProtKB:O89026 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Smad6 SMAD family member 6 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Snx17 sorting nexin 17 ISO
IEA
(MGI:MGI:5644076|PMID:25807483)
GO_REF:0000107
RGD
Ensembl
PMID:25807483 GO_REF:0000107, MGI:MGI:5644076 NCBI chr 6:26,541,137...26,546,650
Ensembl chr 6:26,541,138...26,546,545
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 1:266,143,766...266,241,742
Ensembl chr 1:266,143,818...266,239,016
JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 ISO (MGI:MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:MGI:5644076 NCBI chr 7:121,350,953...121,382,100
Ensembl chr 7:121,350,965...121,382,088
JBrowse link
aorta morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 ISO (MGI:MGI:4452308|PMID:20096780) RGD PMID:20096780 MGI:MGI:4452308 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 ISO MGI:MGI:2176467|MGI:MGI:4433295 (MGI:MGI:5694290|PMID:26102480) RGD PMID:26102480 MGI:MGI:5694290 NCBI chr 5:21,769,087...21,952,036
Ensembl chr 5:21,830,882...21,950,696
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 ISO
IEA
MGI:MGI:102780|MGI:MGI:98493|MGI:MGI:99604 (MGI:MGI:5002778|PMID:21364285)
GO_REF:0000107
RGD
Ensembl
PMID:21364285 GO_REF:0000107, MGI:MGI:5002778 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Fgf8 fibroblast growth factor 8 ISO MGI:MGI:102780|MGI:MGI:109344|MGI:MGI:98493 (MGI:MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:MGI:5002778 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 ISO
IEA
MGI:MGI:5432211 (MGI:MGI:5585367|PMID:24777781)
GO_REF:0000107
RGD
Ensembl
PMID:24777781 GO_REF:0000107, MGI:MGI:5585367 NCBI chr10:88,326,337...88,338,199
Ensembl chr10:88,326,080...88,338,207
JBrowse link
G Foxh1 forkhead box H1 ISO (MGI:MGI:3055632|PMID:15363409) RGD PMID:15363409 MGI:MGI:3055632 NCBI chr 7:117,730,307...117,733,076
Ensembl chr 7:117,730,307...117,732,387
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO (MGI:MGI:4453944|PMID:20122914) RGD PMID:20122914 MGI:MGI:4453944 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO
IEA
(MGI:MGI:4359139|PMID:19509466)
GO_REF:0000107
RGD
Ensembl
PMID:19509466 GO_REF:0000107, MGI:MGI:4359139 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Kat6a lysine acetyltransferase 6A ISO MGI:MGI:4418468|MGI:MGI:98493 (MGI:MGI:5442217|PMID:22921202) RGD PMID:22921202 MGI:MGI:5442217 NCBI chr16:73,942,669...74,020,750
Ensembl chr16:73,943,455...74,023,005
JBrowse link
G Lrp1 LDL receptor related protein 1 ISO (MGI:MGI:4365879|PMID:19742316) RGD PMID:19742316 MGI:MGI:4365879 NCBI chr 7:70,846,313...70,927,028
Ensembl chr 7:70,846,344...70,926,903
JBrowse link
G Nprl3 NPR3-like, GATOR1 complex subunit ISO MGI:MGI:5426855 (MGI:MGI:5319707|PMID:22538705) RGD PMID:22538705 MGI:MGI:5319707 NCBI chr10:15,620,824...15,661,332
Ensembl chr10:15,620,871...15,661,331
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO UniProtKB:Q91ZX7 (MGI:MGI:4365879|PMID:19742316) RGD PMID:19742316 MGI:MGI:4365879 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component ISO MGI:MGI:4440621 (MGI:MGI:4439427|PMID:20215345) RGD PMID:20215345 MGI:MGI:4439427 NCBI chr 2:230,286,886...230,356,887
Ensembl chr 2:230,287,296...230,356,919
JBrowse link
G Six1 SIX homeobox 1 ISO MGI:MGI:109344|MGI:MGI:98493|MGI:MGI:99604 (MGI:MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:MGI:5002778 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296
JBrowse link
G Tbx1 T-box transcription factor 1 ISS
ISO
GO_REF:0000024
MGI:MGI:102780|MGI:MGI:109344|MGI:MGI:3664784|MGI:MGI:99604 (MGI:MGI:3770747|PMID:17916582), (MGI:MGI:5002778|PMID:21364285)
UniProt
RGD
PMID:17916582, PMID:21364285 GO_REF:0000024, MGI:MGI:3770747, MGI:MGI:5002778 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
G Tbx2 T-box transcription factor 2 ISO (MGI:MGI:3487212|PMID:15459098) RGD PMID:15459098 MGI:MGI:3487212 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921
JBrowse link
G Tfap2b transcription factor AP-2 beta ISO
ISS
(MGI:MGI:5287515|PMID:21829553)
GO_REF:0000024
RGD
UniProt
PMID:21829553 GO_REF:0000024, MGI:MGI:5287515 NCBI chr 9:25,410,669...25,440,568
Ensembl chr 9:25,410,669...25,440,411
JBrowse link
aorta smooth muscle tissue morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col3a1 collagen type III alpha 1 chain ISO (MGI:MGI:5307011|PMID:21071432) RGD PMID:21071432 MGI:MGI:5307011 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Mir143 microRNA 143 ISO MGI:MGI:2676830 (MGI:MGI:4443305|PMID:19816508) RGD PMID:19816508 MGI:MGI:4443305 NCBI chr18:56,971,273...56,971,377
Ensembl chr18:56,971,273...56,971,377
JBrowse link
G Mir145 microRNA 145 ISO MGI:MGI:2676828 (MGI:MGI:4443305|PMID:19816508) RGD PMID:19816508 MGI:MGI:4443305 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mylk myosin light chain kinase ISO (PMID:21055718) RGD PMID:21055718 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Prox1 prospero homeobox 1 ISO (MGI:MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:MGI:3830437 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
ascending aorta development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lox lysyl oxidase ISO MGI:MGI:2657016 (MGI:MGI:5912605|PMID:28550176) RGD PMID:28550176 MGI:MGI:5912605 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
ascending aorta morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 ISO
IEA
(MGI:MGI:4354447|PMID:19609448)
GO_REF:0000107
RGD
Ensembl
PMID:19609448 GO_REF:0000107, MGI:MGI:4354447 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO (MGI:MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:MGI:2386835 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Sox4 SRY-box transcription factor 4 ISO (MGI:MGI:3603061|PMID:16109771) RGD PMID:16109771 MGI:MGI:3603061 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:MGI:894212 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
descending aorta development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lox lysyl oxidase ISO MGI:MGI:2657016 (MGI:MGI:5912605|PMID:28550176) RGD PMID:28550176 MGI:MGI:5912605 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
dorsal aorta development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngfr nerve growth factor receptor ISO
IEA
(MGI:MGI:2151307|PMID:11559852)
GO_REF:0000107
RGD
Ensembl
PMID:11559852 GO_REF:0000107, MGI:MGI:2151307 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nkx3-1 NK3 homeobox 1 ISO (PMID:9142502) RGD PMID:9142502 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
dorsal aorta morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 ISO (MGI:MGI:2674189|PMID:12941632) RGD PMID:12941632 MGI:MGI:2674189 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (MGI:MGI:3810850|PMID:18667463) RGD PMID:18667463 MGI:MGI:3810850 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Dll4 delta like canonical Notch ligand 4 ISO (MGI:MGI:3056004|PMID:15466160), (MGI:MGI:3056036|PMID:15466159) RGD PMID:15466159, PMID:15466160 MGI:MGI:3056004, MGI:MGI:3056036 NCBI chr 3:111,135,011...111,146,746
Ensembl chr 3:111,135,021...111,145,986
JBrowse link
G Eng endoglin ISO (MGI:MGI:2674189|PMID:12941632) RGD PMID:12941632 MGI:MGI:2674189 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO UniProtKB:Q9QUS4 (MGI:MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:MGI:3040159 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO UniProtKB:Q9WV93 (MGI:MGI:3040159|PMID:15107403) RGD PMID:15107403 MGI:MGI:3040159 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:3056004|PMID:15466160) RGD PMID:15466160 MGI:MGI:3056004 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Srf serum response factor ISO MGI:MGI:3522206|MGI:MGI:3522214 (MGI:MGI:3513738|PMID:15569937) RGD PMID:15569937 MGI:MGI:3513738 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
positive regulation of aorta morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efnb2 ephrin B2 ISO MGI:MGI:2176476|MGI:MGI:3526818 (MGI:MGI:3832108|PMID:18952909) RGD PMID:18952909 MGI:MGI:3832108 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Ephb4 EPH receptor B4 ISO MGI:MGI:2183162 (MGI:MGI:3832108|PMID:18952909) RGD PMID:18952909 MGI:MGI:3832108 NCBI chr12:22,393,338...22,418,332
Ensembl chr12:22,393,330...22,417,980
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:3832108|PMID:18952909) RGD PMID:18952909 MGI:MGI:3832108 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Notch4 notch receptor 4 ISO (MGI:MGI:3832108|PMID:18952909) RGD PMID:18952909 MGI:MGI:3832108 NCBI chr20:4,329,794...4,353,868
Ensembl chr20:4,329,811...4,353,785
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        blood vessel development 735
          artery development 111
            aorta development 67
              aorta morphogenesis + 36
              ascending aorta development + 5
              descending aorta development + 1
              dorsal aorta development + 10
              ventral aorta development + 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            circulatory system development 1224
              vasculature development 772
                blood vessel development 735
                  artery development 111
                    aorta development 67
                      aorta morphogenesis + 36
                      ascending aorta development + 5
                      descending aorta development + 1
                      dorsal aorta development + 10
                      ventral aorta development + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.