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ONTOLOGY REPORT - ANNOTATIONS


Term:foramen ovale closure
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Accession:GO:0035922 term browser browse the term
Definition:The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.
Synonyms:exact_synonym: foramen ovale of heart closure


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foramen ovale closure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 ISO MGI:2445238 (MGI:3639795|PMID:10969038) RGD PMID:10969038 MGI:3639795 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (PMID:19762328) RGD PMID:19762328 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link

Term paths to the root
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  biological_process 20020
    developmental process 6826
      anatomical structure morphogenesis 2879
        foramen ovale closure 2
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              heart development 687
                cardiac chamber development 198
                  cardiac septum development 129
                    cardiac septum morphogenesis 86
                      foramen ovale closure 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.