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ONTOLOGY REPORT - ANNOTATIONS


Term:tendon cell differentiation
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Accession:GO:0035990 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.
Synonyms:exact_synonym: muscle attachment cell differentiation
 related_synonym: tenocyte differentiation


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tendon cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IMP (MGI:4418577|PMID:20059955) UniProt PMID:20059955 MGI:4418577 NCBI chr14:46,383,525...46,390,669
Ensembl chr14:46,383,520...46,390,669
JBrowse link
G Mkx mohawk homeobox IMP (MGI:5287220|PMID:20696843) MGI PMID:20696843 MGI:5287220 NCBI chr18:6,934,966...7,004,779
Ensembl chr18:6,934,518...7,004,780
JBrowse link
G Scx scleraxis IMP (MGI:3715390|PMID:17567668), (MGI:4418577|PMID:20059955) UniProt PMID:17567668, PMID:20059955 MGI:3715390, MGI:4418577 NCBI chr15:76,457,411...76,459,468
Ensembl chr15:76,457,452...76,459,458
JBrowse link
G Tnmd tenomodulin ISO PMID:21412429 UniProt PMID:21412429 RGD:8553701 NCBI chr  X:133,851,008...133,865,577
Ensembl chr  X:133,850,980...133,865,577
JBrowse link
positive regulation of tendon cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdf7 growth differentiation factor 7 IDA (MGI:5294519|PMID:21412429) UniProt PMID:21412429 MGI:5294519 NCBI chr12:8,297,918...8,301,954
Ensembl chr12:8,297,918...8,301,954
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23386
    cellular process 17420
      cellular developmental process 4666
        cell differentiation 4559
          tendon cell differentiation 5
            negative regulation of tendon cell differentiation 0
            positive regulation of tendon cell differentiation 1
            regulation of tendon cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 23386
    developmental process 7030
      anatomical structure development 6504
        tissue development 2139
          connective tissue development 308
            tendon development 8
              tendon formation 5
                tendon cell differentiation 5
                  negative regulation of tendon cell differentiation 0
                  positive regulation of tendon cell differentiation 1
                  regulation of tendon cell differentiation + 1
paths to the root

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