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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of transcription from RNA polymerase II promoter in response to stress
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Accession:GO:0036003 term browser browse the term
Definition:Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


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positive regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcn1 GCN1 activator of EIF2AK4 ISO (MGI:MGI:5576818|PMID:24333428) RGD PMID:24333428 MGI:MGI:5576818 NCBI chr12:46,728,684...46,789,696
Ensembl chr12:46,728,699...46,789,726
JBrowse link
G Klf2 Kruppel-like factor 2 ISO (PMID:23043106) RGD PMID:23043106 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO (PMID:23043106) RGD PMID:23043106 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Muc1 mucin 1, cell surface associated ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 ISO (MGI:MGI:4820675|PMID:20385086), (MGI:MGI:6107583|PMID:11342101), (MGI:MGI:6316451|PMID:10601325) RGD PMID:10601325, PMID:11342101, PMID:20385086 MGI:MGI:4820675, MGI:MGI:6107583, MGI:MGI:6316451 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:5883206|PMID:22262176)
(PMID:30089260)
RGD PMID:22262176, PMID:30089260 MGI:MGI:5883206 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 ISO (PMID:24939851) RGD PMID:24939851 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 ISO
IBA
(PMID:12871976), (PMID:21113145)
PMID:21873635
(MGI:MGI:5433837|PMID:21113145), (MGI:MGI:5613480|PMID:12871976)
RGD PMID:12871976, PMID:21113145, PMID:21873635 MGI:MGI:5433837, MGI:MGI:5613480, RGD:13792537 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 ISO (PMID:11163209), (PMID:11256944), (PMID:16469704) RGD PMID:11163209, PMID:11256944, PMID:16469704 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atf6b activating transcription factor 6 beta ISO (PMID:11256944) RGD PMID:11256944 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO (PMID:15775988) RGD PMID:15775988 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 IMP
ISO
PMID:15665855
(MGI:MGI:5616321|PMID:15665855)
RGD PMID:15665855, PMID:15665855 MGI:MGI:5616321, RGD:1558627 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 ISO (PMID:16469704)
(MGI:MGI:5616319|PMID:16469704)
RGD PMID:16469704 MGI:MGI:5616319 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IDA
IBA
ISO
IEA
PMID:8657121
PMID:21873635
UniProtKB:P17676 (PMID:15322075), (PMID:15775988), (PMID:22761832), (PMID:24939851)
GO_REF:0000107
(MGI:MGI:3525819|PMID:15601821)
RGD
Ensembl
PMID:15322075, PMID:15601821, PMID:15775988, PMID:22761832, PMID:24939851, PMID:8657121, PMID:21873635 GO_REF:0000107, MGI:MGI:3525819, RGD:1599740, RGD:13792537 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) RGD PMID:14729979 MGI:MGI:3722921 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 ISO
IBA
UniProtKB:O54862 (PMID:11163209)
PMID:21873635
RGD PMID:11163209, PMID:21873635 RGD:13792537 NCBI chr  X:40,258,933...40,309,047
Ensembl chr  X:40,258,493...40,310,563
JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:5621265|PMID:16407291) RGD PMID:16407291 MGI:MGI:5621265 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 ISO (PMID:10747973), (PMID:12659875), (PMID:12665592), (PMID:15016915), (PMID:25963659), (PMID:26754925), (PMID:7760831), (PMID:9499401) RGD PMID:7760831, PMID:9499401, PMID:10747973, PMID:12659875, PMID:12665592, PMID:15016915, PMID:25963659, PMID:26754925 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha IEA
ISO
ISS
GO_REF:0000107
(PMID:19652095), (PMID:22735262), (PMID:24681946)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19652095, PMID:22735262, PMID:24681946 GO_REF:0000024, GO_REF:0000107 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 ISO (PMID:24844779) RGD PMID:24844779 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Notch1 notch receptor 1 ISO
ISS
(MGI:MGI:5319604|PMID:18299578)
GO_REF:0000024
RGD
UniProt
PMID:18299578 GO_REF:0000024, MGI:MGI:5319604 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (PMID:23303788) RGD PMID:23303788 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:MGI:4867601 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vegfa vascular endothelial growth factor A ISO (PMID:19652095) RGD PMID:19652095 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 ISO
IBA
IMP
(PMID:21113145)
PMID:21873635
PMID:23392669
RGD PMID:21113145, PMID:21873635, PMID:23392669 RGD:13792537, RGD:10047168 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Chd6 chromodomain helicase DNA binding protein 6 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16314513)
Ensembl
UniProt
RGD
PMID:16314513 GO_REF:0000024, GO_REF:0000107 NCBI chr 3:156,937,746...157,099,328
Ensembl chr 3:156,937,733...157,099,306
JBrowse link
G Mt3 metallothionein 3 ISO
ISS
(PMID:18554677)
GO_REF:0000024
RGD
UniProt
PMID:18554677 GO_REF:0000024 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 IMP PMID:16314513 UniProt PMID:16314513 RGD:8655528 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Sesn2 sestrin 2 ISO (PMID:23274085) RGD PMID:23274085 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    response to stimulus 10568
      response to stress 4059
        cellular response to stress 1992
          regulation of DNA-templated transcription in response to stress 55
            regulation of transcription from RNA polymerase II promoter in response to stress 51
              positive regulation of transcription from RNA polymerase II promoter in response to stress 25
                positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH 0
                positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation 0
                positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance 0
                positive regulation of transcription from RNA polymerase II promoter in response to cold + 0
                positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 11
                positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation 0
                positive regulation of transcription from RNA polymerase II promoter in response to heat stress 1
                positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure 0
                positive regulation of transcription from RNA polymerase II promoter in response to hypoxia 6
                positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation 0
                positive regulation of transcription from RNA polymerase II promoter in response to menadione 0
                positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress 0
                positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress + 5
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        cellular aromatic compound metabolic process 5708
          nucleobase-containing compound metabolic process 5483
            nucleic acid metabolic process 4980
              RNA metabolic process 4470
                RNA biosynthetic process 3478
                  regulation of RNA biosynthetic process 3343
                    regulation of nucleic acid-templated transcription 3338
                      regulation of transcription, DNA-templated 3289
                        positive regulation of transcription, DNA-templated 1698
                          positive regulation of transcription by RNA polymerase II 1390
                            positive regulation of transcription from RNA polymerase II promoter in response to stress 25
                              positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH 0
                              positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation 0
                              positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance 0
                              positive regulation of transcription from RNA polymerase II promoter in response to cold + 0
                              positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 11
                              positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation 0
                              positive regulation of transcription from RNA polymerase II promoter in response to heat stress 1
                              positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure 0
                              positive regulation of transcription from RNA polymerase II promoter in response to hypoxia 6
                              positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation 0
                              positive regulation of transcription from RNA polymerase II promoter in response to menadione 0
                              positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress 0
                              positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.