ONTOLOGY REPORT - ANNOTATIONS


Term:cleavage furrow formation
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Accession:GO:0036089 term browser browse the term
Definition:Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.
Comment:Consider also annotating to 'establishment of contractile ring localization involved in cell cycle cytokinesis ; GO:0032188'.
Synonyms:narrow_synonym: cleavage furrow positioning


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cleavage furrow formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:730040
RGD:1600115
RGD:1624291
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1624291
RGD:1600115
G Snx18 sorting nexin 18 JBrowse link 2 45,454,782 45,480,798 RGD:1624291
RGD:1600115
G Snx33 sorting nexin 33 JBrowse link 8 61,584,656 61,596,055 RGD:1624291
RGD:1600115
G Snx9 sorting nexin 9 JBrowse link 1 46,780,142 46,826,250 RGD:1624291
RGD:1600115
G Spire1 spire-type actin nucleation factor 1 JBrowse link 18 63,226,557 63,357,420 RGD:1624291
G Spire2 spire-type actin nucleation factor 2 JBrowse link 19 56,136,904 56,175,500 RGD:1624291
RGD:1600115
mitotic cleavage furrow formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    cellular process 16077
      cell cycle process 1129
        cytokinetic process 40
          cleavage furrow formation 7
            mitotic cleavage furrow formation 1
Path 2
Term Annotations click to browse term
  biological_process 17926
    cellular process 16077
      cell cycle 1458
        cell cycle process 1129
          cytokinesis 165
            cytokinetic process 40
              cleavage furrow formation 7
                mitotic cleavage furrow formation 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.