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ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor beta1 activation
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Accession:GO:0036364 term browser browse the term
Definition:The release of transforming growth factor beta1 (TGF-beta1) from its latent state.
Synonyms:exact_synonym: L-TGF-beta 1 activation;   TGF-beta 1 activation;   TGFB1 activation;   TGFbeta 1 activation;   latent-TGF-beta1 activation


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transforming growth factor beta1 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrros negative regulator of reactive oxygen species ISS
ISO
GO_REF:0000024
(MGI:MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024, MGI:MGI:6192878 NCBI chr11:71,872,728...71,889,897
Ensembl chr11:71,872,830...71,889,887
JBrowse link
negative regulation of transforming growth factor beta1 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp1a FKBP prolyl isomerase 1A ISO (PMID:11583628) RGD PMID:11583628 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
positive regulation of transforming growth factor beta1 activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Furin furin (paired basic amino acid cleaving enzyme) ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:7737999)
UniProt
Ensembl
RGD
PMID:7737999 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    multicellular organismal process 9068
      transforming growth factor beta activation 11
        transforming growth factor beta1 activation 3
          negative regulation of transforming growth factor beta1 activation 1
          positive regulation of transforming growth factor beta1 activation 1
          regulation of transforming growth factor beta1 activation + 2
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          gene expression 6294
            cytokine production 838
              transforming growth factor beta production 44
                transforming growth factor beta1 production 12
                  transforming growth factor beta1 activation 3
                    negative regulation of transforming growth factor beta1 activation 1
                    positive regulation of transforming growth factor beta1 activation 1
                    regulation of transforming growth factor beta1 activation + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.