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ONTOLOGY REPORT - ANNOTATIONS


Term:transcription factor catabolic process
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Accession:GO:0036369 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
Synonyms:exact_synonym: proteasome-mediated transcription factor catabolism;   sequence-specific DNA binding transcription factor catabolic process;   transcription factor breakdown;   transcription factor catabolism;   transcription factor degradation


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transcription factor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Taf1 TATA-box binding protein associated factor 1 JBrowse link X 71,412,291 71,486,456 RGD:1624291
positive regulation of transcription factor catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxw8 F-box and WD repeat domain containing 8 JBrowse link 12 44,046,204 44,138,138 RGD:1624291
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:1624291
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:1600115
RGD:1624291
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      primary metabolic process 10563
        protein metabolic process 6070
          protein catabolic process 970
            proteasomal protein catabolic process 478
              proteasome-mediated ubiquitin-dependent protein catabolic process 412
                transcription factor catabolic process 5
                  negative regulation of transcription by transcription factor catabolism 0
                  negative regulation of transcription factor catabolic process 0
                  positive regulation of transcription factor catabolic process 4
                  regulation of transcription factor catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      nitrogen compound metabolic process 10025
        organonitrogen compound metabolic process 6969
          organonitrogen compound catabolic process 1282
            protein catabolic process 970
              cellular protein catabolic process 804
                proteolysis involved in cellular protein catabolic process 751
                  modification-dependent protein catabolic process 639
                    ubiquitin-dependent protein catabolic process 628
                      proteasome-mediated ubiquitin-dependent protein catabolic process 412
                        transcription factor catabolic process 5
                          negative regulation of transcription by transcription factor catabolism 0
                          negative regulation of transcription factor catabolic process 0
                          positive regulation of transcription factor catabolic process 4
                          regulation of transcription factor catabolic process + 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.