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ONTOLOGY REPORT - ANNOTATIONS


Term:arachidonate 8(S)-lipoxygenase activity
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Accession:GO:0036403 term browser browse the term
Definition:Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.
Comment:This activity produces the S-enantiomer of HPETE, 8(S)-HPETE. For the reaction producing the S-enantiomer, see GO:0047677.
Synonyms:broad_synonym: 8(S)-lipoxygenase activity;   8-lipoxygenase (S-type)
 xref: EC:1.13.11;   KEGG_REACTION:R07053;   RHEA:38675


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arachidonate 8(S)-lipoxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:1600115
RGD:1624291

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  molecular_function 19678
    catalytic activity 6023
      oxidoreductase activity 848
        dioxygenase activity 79
          oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 27
            arachidonate 8(S)-lipoxygenase activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.