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ONTOLOGY REPORT - ANNOTATIONS


Term:ESCRT complex
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Accession:GO:0036452 term browser browse the term
Definition:An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes.
Synonyms:exact_synonym: endosomal sorting complex required for transport
 xref: Wikipedia:ESCRT


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ESCRT I complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mvb12a multivesicular body subunit 12A JBrowse link 16 19,973,611 19,978,479 RGD:1624291
RGD:13792537
G Mvb12b multivesicular body subunit 12B JBrowse link 3 12,780,196 12,944,542 RGD:1624291
RGD:13792537
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1600115
RGD:1624291
G Ubap1 ubiquitin-associated protein 1 JBrowse link 5 57,738,309 57,778,724 RGD:1624291
RGD:13792537
RGD:1600115
G Ubap1l ubiquitin associated protein 1-like JBrowse link 8 70,876,516 70,895,723 RGD:13792537
G Vps28 VPS28 subunit of ESCRT-I JBrowse link 7 117,684,339 117,688,187 RGD:1600115
RGD:13792537
RGD:1624291
G Vps37a VPS37A subunit of ESCRT-I JBrowse link 16 54,860,811 54,899,410 RGD:1624291
RGD:13792537
G Vps37b VPS37B subunit of ESCRT-I JBrowse link 12 37,984,790 38,023,369 RGD:1624291
RGD:13792537
G Vps37c VPS37C subunit of ESCRT-I JBrowse link 1 226,742,267 226,774,109 RGD:1624291
RGD:13792537
G Vps37d VPS37D subunit of ESCRT-I JBrowse link 12 24,651,342 24,656,793 RGD:1624291
RGD:13792537
ESCRT II complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snf8 SNF8 subunit of ESCRT-II JBrowse link 10 83,856,331 83,868,621 RGD:1624291
RGD:13792537
G Vps25 vacuolar protein sorting 25 homolog JBrowse link 10 89,174,684 89,180,165 RGD:1624291
RGD:13792537
G Vps36 vacuolar protein sorting 36 homolog JBrowse link 16 74,719,642 74,743,921 RGD:1600115
RGD:13792537
RGD:1624291
ESCRT III complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chmp1a charged multivesicular body protein 1A JBrowse link 19 56,001,724 56,010,004 RGD:13792537
G Chmp1b charged multivesicular body protein 1B JBrowse link 18 62,923,620 62,926,150 RGD:1624291
G Chmp2a charged multivesicular body protein 2A JBrowse link 1 65,540,808 65,543,708 RGD:13792537
RGD:1624291
G Chmp2b charged multivesicular body protein 2B JBrowse link 11 2,666,405 2,692,213 RGD:1624291
RGD:13792537
G Chmp3 charged multivesicular body protein 3 JBrowse link 4 99,449,213 99,496,156 RGD:4892661
RGD:1624291
RGD:13792537
G Chmp4b charged multivesicular body protein 4B JBrowse link 3 150,188,275 150,227,453 RGD:1624291
RGD:13792537
G Chmp4bl1 chromatin modifying protein 4B-like 1 JBrowse link 4 67,059,939 67,060,988 RGD:13792537
G Chmp4c charged multivesicular body protein 4C JBrowse link 2 93,574,554 93,641,497 RGD:13792537
G Chmp6 charged multivesicular body protein 6 JBrowse link 10 109,073,678 109,079,348 RGD:1624291
RGD:13792537
G Chmp7 charged multivesicular body protein 7 JBrowse link 15 51,385,373 51,400,606 RGD:1624291
RGD:13792537
G RGD1566265 similar to RIKEN cDNA 2610002M06 JBrowse link X 78,870,964 78,911,601 RGD:13792537
ESCRT-0 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate JBrowse link 10 109,638,944 109,657,460 RGD:1600115
RGD:1624291
G Stam signal transducing adaptor molecule JBrowse link 17 81,209,795 81,256,111 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19949
    protein-containing complex 5829
      ESCRT complex 26
        ESCRT I complex 10
        ESCRT II complex 3
        ESCRT III complex 11
        ESCRT IV complex 0
        ESCRT-0 complex 2
Path 2
Term Annotations click to browse term
  cellular_component 19949
    cellular anatomical entity 19598
      organelle 12670
        membrane-bounded organelle 10978
          vesicle 1996
            intracellular vesicle 1839
              cytoplasmic vesicle 1834
                endosome 835
                  ESCRT complex 26
                    ESCRT I complex 10
                    ESCRT II complex 3
                    ESCRT III complex 11
                    ESCRT IV complex 0
                    ESCRT-0 complex 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.