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ONTOLOGY REPORT - ANNOTATIONS


Term:intrinsic apoptotic signaling pathway in response to hydrogen peroxide
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Accession:GO:0036481 term browser browse the term
Definition:A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2).
Synonyms:exact_synonym: hydrogen peroxide-induced intrinsic apoptotic signaling pathway;   intrinsic apoptotic signaling pathway in response to H2O2
 broad_synonym: hydrogen peroxide-induced apoptosis
 related_synonym: H2O2-induced intrinsic apoptotic signaling pathway


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intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdcd10 programmed cell death 10 JBrowse link 2 173,966,701 174,012,730 RGD:1624291
RGD:1600115
G Stk25 serine/threonine kinase 25 JBrowse link 9 100,767,578 100,779,715 RGD:1624291
RGD:1600115
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
RGD:1600115
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsph1 heat shock protein family H (Hsp110) member 1 JBrowse link 12 6,322,685 6,341,898 RGD:1624291
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:8693356
RGD:1624291
G Trap1 TNF receptor-associated protein 1 JBrowse link 10 11,724,032 11,757,682 RGD:8693356

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19312
    cellular process 17222
      cell death 2145
        cell death in response to oxidative stress 101
          intrinsic apoptotic signaling pathway in response to oxidative stress 45
            intrinsic apoptotic signaling pathway in response to hydrogen peroxide 6
              negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 4
              neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 2
              positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide 0
              regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 4
Path 2
Term Annotations click to browse term
  biological_process 19312
    response to stimulus 10391
      response to stress 3952
        response to oxidative stress 533
          response to reactive oxygen species 301
            cellular response to reactive oxygen species 204
              cellular response to hydrogen peroxide 127
                cell death in response to hydrogen peroxide 39
                  hydrogen peroxide-mediated programmed cell death 15
                    intrinsic apoptotic signaling pathway in response to hydrogen peroxide 6
                      negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 4
                      neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 2
                      positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide 0
                      regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide + 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.