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ONTOLOGY REPORT - ANNOTATIONS


Term:opioid receptor signaling pathway
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Accession:GO:0038003 term browser browse the term
Definition:The series of molecular signals generated as a consequence of an opioid receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: opioid receptor signalling pathway


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opioid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 IDA PMID:16186630 UniProt PMID:16186630 RGD:13825193 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Ogfr opioid growth factor receptor IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:176,093,662...176,099,949
Ensembl chr 3:175,930,505...176,099,987
JBrowse link
G Ogfrl1 opioid growth factor receptor-like 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:29,634,178...29,647,903
Ensembl chr 9:29,634,179...29,647,903
JBrowse link
G Oprd1 opioid receptor, delta 1 ISO
IBA
(PMID:9548483)
PMID:21873635
RGD PMID:9548483, PMID:21873635 RGD:13792537 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Oprk1 opioid receptor, kappa 1 ISO
IBA
(PMID:8755601)
PMID:21873635
RGD PMID:8755601, PMID:21873635 RGD:13792537 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IEA
ISO
GO_REF:0000108
(PMID:10571060)
GOC
RGD
PMID:10571060 GO_REF:0000108 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Oprm1 opioid receptor, mu 1 IDA
IBA
IEA
PMID:21873635
GO_REF:0000108
GOC PMID:19172190, PMID:21873635 GO_REF:0000108, RGD:7207406, RGD:13792537 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:58,121,824...58,124,687
Ensembl chr 5:58,121,786...58,124,681
JBrowse link
adenylate cyclase-inhibiting opioid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprk1 opioid receptor, kappa 1 ISO
ISS
(PMID:22437504)
GO_REF:0000024
RGD
UniProt
PMID:22437504 GO_REF:0000024 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:17157995 RGD:1625132 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 IMP RGD PMID:17157995 RGD:1625132 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
regulation of opioid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B ISS
ISO
GO_REF:0000024
(MGI:3834288|PMID:18439408)
UniProt
RGD
PMID:18439408 GO_REF:0000024, MGI:3834288 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731
JBrowse link
G Syp synaptophysin IDA PMID:17005904 UniProt PMID:17005904 RGD:8554727 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    signaling 7579
      signal transduction 7010
        G protein-coupled receptor signaling pathway 2509
          opioid receptor signaling pathway 11
            adenylate cyclase-inhibiting opioid receptor signaling pathway + 3
            negative regulation of opioid receptor signaling pathway + 0
            positive regulation of opioid receptor signaling pathway + 1
            regulation of opioid receptor signaling pathway + 3
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          signal transduction 7010
            G protein-coupled receptor signaling pathway 2509
              opioid receptor signaling pathway 11
                adenylate cyclase-inhibiting opioid receptor signaling pathway + 3
                negative regulation of opioid receptor signaling pathway + 0
                positive regulation of opioid receptor signaling pathway + 1
                regulation of opioid receptor signaling pathway + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.