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ONTOLOGY REPORT - ANNOTATIONS


Term:cross-receptor inhibition within G protein-coupled receptor heterodimer
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Accession:GO:0038041 term browser browse the term
Definition:Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.


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cross-receptor inhibition within G protein-coupled receptor heterodimer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcr calcitonin receptor ISO UniProtKB:O60896 (PMID:14722252) RGD PMID:14722252 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
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G Ramp3 receptor activity modifying protein 3 ISO UniProtKB:P30988 (PMID:14722252) RGD PMID:14722252 NCBI chr14:86,922,223...86,939,722
Ensembl chr14:86,922,223...86,939,719
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      signal transduction 7010
        G protein-coupled receptor signaling pathway 2509
          regulation of G protein-coupled receptor signaling pathway 132
            cross-receptor inhibition within G protein-coupled receptor heterodimer 2
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          regulation of cell communication 3480
            regulation of signal transduction 2934
              regulation of signaling receptor activity 189
                negative regulation of signaling receptor activity 54
                  cross-receptor inhibition within G protein-coupled receptor heterodimer 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.