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ONTOLOGY REPORT - ANNOTATIONS


Term:transforming growth factor-beta secretion
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Accession:GO:0038044 term browser browse the term
Definition:The regulated release of transforming growth factor-beta (TGF-beta) from a cell into the extracellular region. TGF-beta is mostly secreted as a large latent TGF-beta complex (LLC) containing latency-associated proteins (LAPs) derived from the N-terminal region of the TGF-beta gene product, dimeric TGF-beta and latent TGF-beta binding proteins (LTBPs).
Synonyms:exact_synonym: TGF-beta secretion;   TGFbeta secretion


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transforming growth factor-beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itgav integrin subunit alpha V JBrowse link 3 71,113,269 71,205,958 RGD:1624291
RGD:1600115
G Itgb6 integrin subunit beta 6 JBrowse link 3 46,652,624 46,775,362 RGD:1624291
RGD:1600115
negative regulation of transforming growth factor-beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbln1 fibulin 1 JBrowse link 7 126,096,793 126,176,468 RGD:1624291
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:1600115
RGD:1624291
positive regulation of transforming growth factor-beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fermt1 fermitin family member 1 JBrowse link 3 125,566,744 125,607,864 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    multicellular organismal process 8749
      cytokine production 797
        cytokine secretion 272
          transforming growth factor-beta secretion 5
            negative regulation of transforming growth factor-beta secretion 2
            positive regulation of transforming growth factor-beta secretion 1
            regulation of transforming growth factor-beta secretion + 3
Path 2
Term Annotations click to browse term
  biological_process 19245
    localization 6273
      establishment of localization 4844
        transport 4705
          nitrogen compound transport 2235
            amide transport 1913
              peptide transport 1880
                protein transport 1822
                  protein secretion 651
                    cytokine secretion 272
                      transforming growth factor-beta secretion 5
                        negative regulation of transforming growth factor-beta secretion 2
                        positive regulation of transforming growth factor-beta secretion 1
                        regulation of transforming growth factor-beta secretion + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.