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ONTOLOGY REPORT - ANNOTATIONS


Term:sequestering of nodal from receptor via nodal binding
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Accession:GO:0038101 term browser browse the term
Definition:Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.
Synonyms:exact_synonym: binding to and sequestering nodal
 broad_synonym: extracellular regulation of nodal;   nodal antagonist activity


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sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain BMP antagonist family member 5 ISO (MGI:MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:MGI:3055649 NCBI chr19:25,929,704...25,937,852
Ensembl chr19:25,930,601...25,936,026
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      signal transduction 7011
        negative regulation of signal transduction 1235
          extracellular negative regulation of signal transduction 11
            sequestering of extracellular ligand from receptor 10
              sequestering of nodal from receptor via nodal binding 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological process 13075
        regulation of cellular process 12561
          signal transduction 7011
            cell surface receptor signaling pathway 2761
              enzyme linked receptor protein signaling pathway 969
                transmembrane receptor protein serine/threonine kinase signaling pathway 387
                  activin receptor signaling pathway 47
                    regulation of activin receptor signaling pathway 28
                      negative regulation of activin receptor signaling pathway 13
                        negative regulation of nodal signaling pathway 4
                          sequestering of nodal from receptor via nodal binding 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.