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ONTOLOGY REPORT - ANNOTATIONS


Term:neuregulin receptor activity
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Accession:GO:0038131 term browser browse the term
Definition:Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Comment:Consider also annotating to 'ERBB3 signaling pathway ; GO:0038129' and/or 'ERBB4 signaling pathway ; GO:0038130'.
Synonyms:exact_synonym: NRG receptor activity
 narrow_synonym: NRG1 receptor activity;   NRG2 receptor activity


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neuregulin receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb3 erb-b2 receptor tyrosine kinase 3 IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:14711829, PMID:21873635 RGD:2289958, RGD:13792537 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Rtn4r reticulon 4 receptor ISO
ISS
(MGI:MGI:5688832|PMID:22923615)
GO_REF:0000024
RGD
UniProt
PMID:22923615 GO_REF:0000024, MGI:MGI:5688832 NCBI chr11:86,992,665...87,017,091
Ensembl chr11:86,992,399...87,017,115
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    molecular transducer activity 2656
      signaling receptor activity 2656
        transmembrane signaling receptor activity 2499
          neuregulin receptor activity 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.