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ONTOLOGY REPORT - ANNOTATIONS


Term:granulocyte colony-stimulating factor signaling pathway
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Accession:GO:0038158 term browser browse the term
Definition:A series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R).
Synonyms:exact_synonym: CSF3 signaling pathway;   G-CSF receptor signaling pathway;   G-CSF signaling pathway;   granulocyte colony-stimulating factor receptor signaling pathway
 related_synonym: granulocyte colony-stimulating factor signalling pathway


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granulocyte colony-stimulating factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 ISS
ISO
GO_REF:0000024
(MGI:4837548|PMID:21029969)
UniProt
RGD
PMID:21029969 GO_REF:0000024, MGI:4837548 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr14:1,462,292...1,467,264
Ensembl chr14:1,462,358...1,467,264
JBrowse link
G Jagn1 jagunal homolog 1 ISO
ISS
(PMID:25129144)
(MGI:5604054|PMID:25129145)
GO_REF:0000024
RGD
UniProt
PMID:25129144, PMID:25129145 GO_REF:0000024, MGI:5604054 NCBI chr 4:145,399,885...145,404,605
Ensembl chr 4:145,399,913...145,404,617
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    signaling 7579
      signal transduction 7010
        cell surface receptor signaling pathway 2761
          cytokine-mediated signaling pathway 406
            granulocyte colony-stimulating factor signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 20020
    response to stimulus 10580
      response to chemical 6337
        response to organic substance 3864
          cellular response to organic substance 2844
            cellular response to cytokine stimulus 998
              cytokine-mediated signaling pathway 406
                granulocyte colony-stimulating factor signaling pathway 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.