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ONTOLOGY REPORT - ANNOTATIONS


Term:prolactin signaling pathway
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Accession:GO:0038161 term browser browse the term
Definition:A series of molecular signals initiated by the binding of the peptide hormone prolactin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PRL signaling pathway;   prolactin-mediated signaling pathway


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prolactin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prlr prolactin receptor IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
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positive regulation of prolactin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor ISO (MGI:MGI:5466657|PMID:23071095) RGD PMID:23071095 MGI:MGI:5466657 NCBI chr10:16,693,846...16,753,162
Ensembl chr10:16,694,792...16,752,205
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    signaling 7583
      signal transduction 7011
        hormone-mediated signaling pathway 186
          prolactin signaling pathway 2
            negative regulation of prolactin signaling pathway 0
            positive regulation of prolactin signaling pathway 1
            regulation of prolactin signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      cellular response to stimulus 8920
        cellular response to chemical stimulus 3528
          cellular response to organic substance 2845
            cellular response to hormone stimulus 758
              hormone-mediated signaling pathway 186
                prolactin signaling pathway 2
                  negative regulation of prolactin signaling pathway 0
                  positive regulation of prolactin signaling pathway 1
                  regulation of prolactin signaling pathway + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.