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ONTOLOGY REPORT - ANNOTATIONS


Term:erythropoietin-mediated signaling pathway
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Accession:GO:0038162 term browser browse the term
Definition:A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: EPO-R signaling pathway;   erythropoietin receptor signaling pathway


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erythropoietin-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin ISO
IBA
ISS
(PMID:28283061)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:28283061, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO (MGI:MGI:5430888|PMID:18538998) RGD PMID:18538998 MGI:MGI:5430888 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    signaling 7583
      signal transduction 7011
        cell surface receptor signaling pathway 2761
          cytokine-mediated signaling pathway 406
            erythropoietin-mediated signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to chemical 6343
        response to organic substance 3865
          cellular response to organic substance 2845
            cellular response to cytokine stimulus 998
              cytokine-mediated signaling pathway 406
                erythropoietin-mediated signaling pathway 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.