Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:oncostatin-M-mediated signaling pathway
go back to main search page
Accession:GO:0038165 term browser browse the term
Definition:A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
Synonyms:exact_synonym: OSM signaling pathway;   oncostatin-M signaling pathway


show annotations for term's descendants           Sort by:
 
oncostatin-M-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il13ra1 interleukin 13 receptor subunit alpha 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479
JBrowse link
G Il6st interleukin 6 signal transducer ISO
IEA
(PMID:8999038)
GO_REF:0000107
RGD
Ensembl
PMID:8999038 GO_REF:0000107 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Lifr LIF receptor subunit alpha ISO
IEA
(PMID:8999038)
GO_REF:0000107
RGD
Ensembl
PMID:8999038 GO_REF:0000107 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link
G LOC100360218 interleukin 13 receptor, alpha 1-like IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:74,864,036...74,866,477
Ensembl chr  X:122,724,129...122,781,479
Ensembl chr11:122,724,129...122,781,479
JBrowse link
G Osm oncostatin M ISO (PMID:8999038) RGD PMID:8999038 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Osmr oncostatin M receptor ISO
IEA
(PMID:8999038)
GO_REF:0000107
RGD
Ensembl
PMID:8999038 GO_REF:0000107 NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531
JBrowse link
G Prlr prolactin receptor IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    signaling 7580
      signal transduction 7011
        cell surface receptor signaling pathway 2761
          cytokine-mediated signaling pathway 406
            oncostatin-M-mediated signaling pathway 7
Path 2
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to chemical 6342
        response to organic substance 3865
          cellular response to organic substance 2845
            cellular response to cytokine stimulus 998
              cytokine-mediated signaling pathway 406
                oncostatin-M-mediated signaling pathway 7
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.