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ONTOLOGY REPORT - ANNOTATIONS


Term:somatostatin receptor signaling pathway
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Accession:GO:0038169 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a somatostatin receptor (SSTR) binding to one of its physiological ligands and transmitting the signal to a heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
Comment:In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'.
Synonyms:exact_synonym: SST receptor signaling pathway
 related_synonym: SSTR signaling pathway


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somatostatin signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sstr1 somatostatin receptor 1 JBrowse link 6 79,252,914 79,258,611 RGD:1600115
G Sstr2 somatostatin receptor 2 JBrowse link 10 102,136,283 102,143,449 RGD:1600115
G Sstr3 somatostatin receptor 3 JBrowse link 7 119,760,881 119,768,082 RGD:1600115
G Sstr4 somatostatin receptor 4 JBrowse link 3 142,739,781 142,741,644 RGD:1600115
G Sstr5 somatostatin receptor 5 JBrowse link 10 14,847,749 14,853,827 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    signaling 7108
      signal transduction 6597
        G protein-coupled receptor signaling pathway 2395
          somatostatin receptor signaling pathway 5
            somatostatin signaling pathway 5
Path 2
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological process 12128
        regulation of cellular process 11458
          signal transduction 6597
            G protein-coupled receptor signaling pathway 2395
              somatostatin receptor signaling pathway 5
                somatostatin signaling pathway 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.