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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of RIG-I signaling pathway
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Accession:GO:0039536 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.
Synonyms:exact_synonym: negative regulation of DDX58 signaling pathway;   negative regulation of RIG-I signalling pathway;   negative regulation of retinoic acid inducible gene I signaling pathway


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negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein IEA Ensembl GO_REF:0000107 NCBI chr 5:31,354,665...31,359,672
Ensembl chr 5:31,354,723...31,359,469
JBrowse link
G DHX58 DExH-box helicase 58 IEA Ensembl GO_REF:0000107 NCBI chr 9:20,787,470...20,795,593
Ensembl chr 9:20,787,541...20,795,361
JBrowse link
G GPATCH3 G-patch domain containing 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:73,243,178...73,250,926
Ensembl chr 2:73,243,222...73,250,403
JBrowse link
G NLRX1 NLR family member X1 IEA Ensembl GO_REF:0000107 NCBI chr 5:14,692,621...14,705,214
Ensembl chr 5:14,564,935...14,705,257
JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor IEA Ensembl GO_REF:0000107 NCBI chr 9:538,087...604,898
Ensembl chr 9:537,840...603,480
JBrowse link
G RNF125 ring finger protein 125 IEA Ensembl GO_REF:0000107 NCBI chr 7:57,570,779...57,607,485
Ensembl chr 7:57,574,738...57,608,017
JBrowse link
G SEC14L1 SEC14 like lipid binding 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:3,683,328...3,740,271
Ensembl chr 9:3,659,451...3,739,213
JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 IEA Ensembl GO_REF:0000107 NCBI chr26:29,739,062...29,763,315
Ensembl chr26:29,739,153...29,763,313
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    immune system process 2294
      immune effector process 706
        defense response to virus 218
          cytoplasmic pattern recognition receptor signaling pathway in response to virus 28
            RIG-I signaling pathway 24
              negative regulation of RIG-I signaling pathway 8
Path 2
Term Annotations click to browse term
  biological_process 16187
    biological regulation 11555
      regulation of biological process 10957
        regulation of cellular process 10499
          signal transduction 5456
            pattern recognition receptor signaling pathway 155
              cytoplasmic pattern recognition receptor signaling pathway 48
                cytoplasmic pattern recognition receptor signaling pathway in response to virus 28
                  regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 19
                    negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 11
                      negative regulation of RIG-I signaling pathway 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.