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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA endoreduplication
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Accession:GO:0042023 term browser browse the term
Definition:Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
Comment:Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states.
Synonyms:exact_synonym: DNA endoreplication;   DNA re-duplication


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DNA endoreduplication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zpr1 ZPR1 zinc finger ISO (MGI:MGI:3575865|PMID:15767679) RGD PMID:15767679 MGI:MGI:3575865 NCBI chr 8:50,563,047...50,572,621
Ensembl chr 8:50,563,047...50,572,621
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 ISO
ISS
(MGI:MGI:5449497|PMID:23064266)
GO_REF:0000024
RGD
UniProt
PMID:23064266 GO_REF:0000024, MGI:MGI:5449497 NCBI chr 7:53,275,659...53,318,261
Ensembl chr 7:53,275,676...53,316,481
JBrowse link
G E2f8 E2F transcription factor 8 IEA
ISO
ISS
GO_REF:0000107
(MGI:MGI:5449497|PMID:23064266), (MGI:MGI:5449498|PMID:23064264)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23064264, PMID:23064266 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5449497, MGI:MGI:5449498 NCBI chr 1:104,185,436...104,203,683
Ensembl chr 1:104,187,100...104,202,591
JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Senp2 SUMO specific peptidase 2 ISO MGI:MGI:3832730 (MGI:MGI:3831588|PMID:19090619) RGD PMID:19090619 MGI:MGI:3831588 NCBI chr11:82,627,973...82,664,702
Ensembl chr11:82,630,436...82,664,630
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell cycle process 1210
        cell cycle DNA replication 42
          DNA endoreduplication 5
            negative regulation of DNA endoreduplication 1
            positive regulation of DNA endoreduplication 2
            regulation of DNA endoreduplication + 4
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          cellular macromolecule metabolic process 8554
            cellular macromolecule biosynthetic process 5074
              DNA replication 257
                DNA-dependent DNA replication 154
                  cell cycle DNA replication 42
                    DNA endoreduplication 5
                      negative regulation of DNA endoreduplication 1
                      positive regulation of DNA endoreduplication 2
                      regulation of DNA endoreduplication + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.