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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cytokine biosynthetic process
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Accession:GO:0042035 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.
Synonyms:exact_synonym: regulation of cytokine anabolism;   regulation of cytokine biosynthesis;   regulation of cytokine formation;   regulation of cytokine synthesis


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regulation of cytokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:1624291
G Zfp287 zinc finger protein 287 JBrowse link 10 49,131,764 49,150,930 RGD:1624291
RGD:13792537
negative regulation of chemokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Sigirr single Ig and TIR domain containing JBrowse link 1 213,898,395 213,907,697 RGD:1624291
RGD:1600115
negative regulation of cytokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Rnf128 ring finger protein 128 JBrowse link X 110,789,061 110,877,964 RGD:1624291
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein JBrowse link 4 118,207,845 118,238,246 RGD:1624291
negative regulation of hepatocyte growth factor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Inhbb inhibin subunit beta B JBrowse link 13 35,436,532 35,442,222 RGD:1600115
RGD:1624291
negative regulation of tumor necrosis factor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:9685562
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624291
RGD:1600115
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:1624291
RGD:1600115
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1598631
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
positive regulation of chemokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:1600115
RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il16 interleukin 16 JBrowse link 1 145,781,923 145,881,538 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1600115
RGD:1624291
positive regulation of cytokine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ereg epiregulin JBrowse link 14 18,577,620 18,591,395 RGD:1624291
RGD:1600115
positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1624291
RGD:1600115
positive regulation of TRAIL biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfrsf8 TNF receptor superfamily member 8 JBrowse link 5 163,186,349 163,231,578 RGD:1624291
positive regulation of tumor necrosis factor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G Akap12 A-kinase anchoring protein 12 JBrowse link 1 40,816,130 40,906,582 RGD:14348968
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
RGD:1600115
G Clec4m C-type lectin domain family 4 member M JBrowse link 12 2,817,633 2,826,303 RGD:1624291
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
RGD:13792537
G Cybb cytochrome b-245 beta chain JBrowse link X 14,578,330 14,610,049 RGD:11040691
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:1624291
RGD:1600115
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:1600115
RGD:1624291
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:1624291
RGD:13792537
RGD:1600115
G Mapkapk2 MAPK activated protein kinase 2 JBrowse link 13 47,785,157 47,871,684 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1624291
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:1624291
RGD:1600115
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tnfrsf8 TNF receptor superfamily member 8 JBrowse link 5 163,186,349 163,231,578 RGD:1624291
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
RGD:13792537
regulation of granulocyte macrophage colony-stimulating factor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il17f interleukin 17F JBrowse link 9 26,885,702 26,897,219 RGD:1600115
RGD:1624291
regulation of tumor necrosis factor biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Card9 caspase recruitment domain family, member 9 JBrowse link 3 3,798,346 3,806,841 RGD:1624291
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:1624291
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 JBrowse link 5 48,274,387 48,292,699 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    multicellular organismal process 8951
      cytokine production 842
        cytokine biosynthetic process 57
          regulation of cytokine biosynthetic process 56
            negative regulation of cytokine biosynthetic process + 13
            positive regulation of cytokine biosynthetic process + 38
            regulation of TRAIL biosynthetic process + 1
            regulation of chemokine biosynthetic process + 16
            regulation of granulocyte macrophage colony-stimulating factor biosynthetic process + 3
            regulation of hepatocyte growth factor biosynthetic process + 1
            regulation of lymphotoxin A biosynthetic process + 0
            regulation of tumor necrosis factor biosynthetic process + 35
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      organic substance metabolic process 11495
        macromolecule metabolic process 9944
          gene expression 6164
            regulation of gene expression 4685
              regulation of cytokine production 759
                regulation of cytokine biosynthetic process 56
                  negative regulation of cytokine biosynthetic process + 13
                  positive regulation of cytokine biosynthetic process + 38
                  regulation of TRAIL biosynthetic process + 1
                  regulation of chemokine biosynthetic process + 16
                  regulation of granulocyte macrophage colony-stimulating factor biosynthetic process + 3
                  regulation of hepatocyte growth factor biosynthetic process + 1
                  regulation of lymphotoxin A biosynthetic process + 0
                  regulation of tumor necrosis factor biosynthetic process + 35
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.