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ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-12 biosynthetic process
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Accession:GO:0042090 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of interleukin-12.
Synonyms:exact_synonym: IL-12 biosynthesis;   IL-12 biosynthetic process;   interleukin-12 anabolism;   interleukin-12 biosynthesis;   interleukin-12 formation;   interleukin-12 synthesis


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negative regulation of interleukin-12 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115
positive regulation of interleukin-12 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
RGD:1600115
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
RGD:1600115
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:1624291
RGD:1600115
G LOC103694381 lymphotoxin-beta JBrowse link 20 4,861,343 4,863,513 RGD:1624291
G Rel REL proto-oncogene, NF-kB subunit JBrowse link 14 108,490,794 108,517,582 RGD:1624291
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:1624291
RGD:1600115
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
RGD:1600115
regulation of interleukin-12 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mast2 microtubule associated serine/threonine kinase 2 JBrowse link 5 135,149,336 135,285,337 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    multicellular organismal process 8585
      cytokine production 783
        cytokine biosynthetic process 116
          interleukin-12 biosynthetic process 11
            negative regulation of interleukin-12 biosynthetic process 1
            positive regulation of interleukin-12 biosynthetic process 9
            regulation of interleukin-12 biosynthetic process + 11
Path 2
Term Annotations click to browse term
  biological_process 18008
    metabolic process 10729
      organic substance metabolic process 10177
        organonitrogen compound metabolic process 6369
          protein metabolic process 5543
            cytokine metabolic process 120
              cytokine biosynthetic process 116
                interleukin-12 biosynthetic process 11
                  negative regulation of interleukin-12 biosynthetic process 1
                  positive regulation of interleukin-12 biosynthetic process 9
                  regulation of interleukin-12 biosynthetic process + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.