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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell receptor complex
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Accession:GO:0042101 term browser browse the term
Definition:A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.
Synonyms:exact_synonym: T lymphocyte receptor complex;   TCR complex
 related_synonym: TCR
 xref: Wikipedia:T_cell_receptor


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T cell receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alcam activated leukocyte cell adhesion molecule colocalizes_with ISO
ISS
(PMID:15294938)
GO_REF:0000024
RGD
UniProt
PMID:15294938 GO_REF:0000024 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein ISO (MGI:MGI:3714085|PMID:17403904) RGD PMID:17403904 MGI:MGI:3714085 NCBI chr17:90,098,953...90,149,192
Ensembl chr17:90,099,025...90,149,894
JBrowse link
G Cd247 Cd247 molecule IDA
ISO
(PMID:8176201) RGD PMID:8176201, PMID:8409430 RGD:634717 NCBI chr13:83,996,045...84,071,408
Ensembl chr13:83,996,080...84,071,400
JBrowse link
G Cd3d CD3d molecule ISO (PMID:8176201) RGD PMID:8176201 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110
JBrowse link
G Cd3e CD3e molecule ISO (PMID:8176201) RGD PMID:8176201 NCBI chr 8:49,297,604...49,309,370
Ensembl chr 8:49,297,608...49,308,806
JBrowse link
G Cd6 Cd6 molecule colocalizes_with ISO (PMID:15294938) RGD PMID:15294938 NCBI chr 1:226,848,399...226,887,259
Ensembl chr 1:226,848,403...226,887,156
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 colocalizes_with ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Skap1 src kinase associated phosphoprotein 1 ISO (MGI:MGI:3714085|PMID:17403904) RGD PMID:17403904 MGI:MGI:3714085 NCBI chr10:84,309,379...84,619,051
Ensembl chr10:84,309,430...84,619,050
JBrowse link
G Stoml2 stomatin like 2 colocalizes_with ISO
ISS
(PMID:18641330)
GO_REF:0000024
RGD
UniProt
PMID:18641330 GO_REF:0000024 NCBI chr 5:58,472,561...58,476,158
Ensembl chr 5:58,472,550...58,476,251
JBrowse link
G Syk spleen associated tyrosine kinase ISO
IEA
(PMID:8176201)
GO_REF:0000107
RGD
Ensembl
PMID:8176201 GO_REF:0000107 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 ISO (PMID:11390434) RGD PMID:11390434 NCBI chr11:54,619,169...54,661,284
Ensembl chr11:54,619,129...54,662,353
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 ISO (PMID:8176201) RGD PMID:8176201 NCBI chr 9:43,331,149...43,353,097
Ensembl chr 9:43,331,155...43,353,113
JBrowse link
alpha-beta T cell receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 Cd247 molecule ISO
IBA
(MGI:MGI:82729|PMID:9064344), (MGI:MGI:893249|PMID:9208839)
PMID:21873635
RGD PMID:9064344, PMID:9208839, PMID:21873635 MGI:MGI:82729, MGI:MGI:893249, RGD:13792537 NCBI chr13:83,996,045...84,071,408
Ensembl chr13:83,996,080...84,071,400
JBrowse link
G Cd3d CD3d molecule ISO
IBA
(MGI:MGI:893249|PMID:9208839)
PMID:21873635
RGD PMID:9208839, PMID:21873635 MGI:MGI:893249, RGD:13792537 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110
JBrowse link
G Cd3e CD3e molecule ISO
IBA
(MGI:MGI:82729|PMID:9064344), (MGI:MGI:893249|PMID:9208839)
PMID:21873635
RGD PMID:9064344, PMID:9208839, PMID:21873635 MGI:MGI:82729, MGI:MGI:893249, RGD:13792537 NCBI chr 8:49,297,604...49,309,370
Ensembl chr 8:49,297,608...49,308,806
JBrowse link
G Cd3g CD3g molecule ISO
IBA
IEA
(MGI:MGI:893249|PMID:9208839)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:9208839, PMID:21873635 GO_REF:0000107, MGI:MGI:893249, RGD:13792537 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 ISO
IEA
(MGI:MGI:82729|PMID:9064344)
GO_REF:0000107
RGD
Ensembl
PMID:9064344 GO_REF:0000107, MGI:MGI:82729 NCBI chr 4:157,239,141...157,263,890
Ensembl chr 4:157,239,142...157,263,890
JBrowse link
gamma-delta T cell receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trg T cell receptor gamma locus TAS RGD PMID:8607875 RGD:634395

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20610
    protein-containing complex 6105
      receptor complex 412
        plasma membrane signaling receptor complex 186
          T cell receptor complex 15
            alpha-beta T cell receptor complex 5
            gamma-delta T cell receptor complex 1
Path 2
Term Annotations click to browse term
  cellular_component 20610
    cellular anatomical entity 20359
      cell periphery 6476
        plasma membrane 6317
          plasma membrane protein complex 566
            plasma membrane signaling receptor complex 186
              T cell receptor complex 15
                alpha-beta T cell receptor complex 5
                gamma-delta T cell receptor complex 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.