Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:neurotransmitter biosynthetic process
go back to main search page
Accession:GO:0042136 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
Synonyms:exact_synonym: neurotransmitter anabolism;   neurotransmitter biosynthesis;   neurotransmitter formation;   neurotransmitter synthesis
 broad_synonym: neurotransmitter biosynthesis and storage;   neurotransmitter biosynthetic process and storage


show annotations for term's descendants       view all columns           Sort by:
 
neurotransmitter biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 JBrowse link 13 85,580,828 85,597,497 RGD:1624291
G Chat choline O-acetyltransferase JBrowse link 16 8,576,858 8,686,131 RGD:1358491
G Dagla diacylglycerol lipase, alpha JBrowse link 1 226,297,013 226,353,712 RGD:1624291
RGD:13792537
G Daglb diacylglycerol lipase, beta JBrowse link 12 13,113,073 13,157,748 RGD:1624291
RGD:13792537
RGD:1600115
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:1600115
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:1600115
acetylcholine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chat choline O-acetyltransferase JBrowse link 16 8,576,858 8,686,131 RGD:2301195
RGD:13792537
RGD:2301203
RGD:2301199
RGD:2301197
G Slc44a4 solute carrier family 44, member 4 JBrowse link 20 4,593,389 4,609,641 RGD:1600115
RGD:1624291
G Slc5a7 solute carrier family 5 member 7 JBrowse link 9 5,294,377 5,330,822 RGD:1624291
RGD:13792537
RGD:1600115
RGD:68853
beta-alanine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:1600115
G Upb1 beta-ureidopropionase 1 JBrowse link 20 14,167,383 14,193,724 RGD:634224
beta-alanine biosynthetic process via 3-ureidopropionate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Upb1 beta-ureidopropionase 1 JBrowse link 20 14,167,383 14,193,724 RGD:13792537
RGD:1600115
RGD:1624291
gamma-aminobutyric acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:9588538
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480258
G Slc1a3 solute carrier family 1 member 3 JBrowse link 2 57,860,881 57,935,363 RGD:1624291
RGD:1600115
glycine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC688286 similar to threonine aldolase 1 JBrowse link 10 106,877,585 106,883,706 RGD:13792537
G Sardh sarcosine dehydrogenase JBrowse link 3 5,737,203 5,802,153 RGD:634034
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:2300383
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:2300383
glycine biosynthetic process from serine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shmt1 serine hydroxymethyltransferase 1 JBrowse link 10 47,030,813 47,059,216 RGD:2300383
RGD:13792537
G Shmt2 serine hydroxymethyltransferase 2 JBrowse link 7 70,824,718 70,829,822 RGD:2300383
RGD:13792537
glycine biosynthetic process, by transamination of glyoxylate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase JBrowse link 9 100,281,339 100,291,292 RGD:1599457
RGD:13792537
RGD:1624291
G Agxt2 alanine-glyoxylate aminotransferase 2 JBrowse link 2 60,337,667 60,379,144 RGD:1624291
histamine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdc histidine decarboxylase JBrowse link 3 119,057,524 119,075,599 RGD:1600115
RGD:1624291
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 JBrowse link 3 72,395,194 72,401,254 RGD:1624291
negative regulation of nitric oxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp5 acid phosphatase 5, tartrate resistant JBrowse link 8 23,142,733 23,149,067 RGD:1624291
RGD:1600115
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:1624291
RGD:1600115
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:633683
G Epor erythropoietin receptor JBrowse link 8 22,969,737 22,974,468 RGD:11041656
G Gimap5 GTPase, IMAP family member 5 JBrowse link 4 78,377,228 78,386,683 RGD:2303775
G Gla galactosidase, alpha JBrowse link X 105,405,915 105,417,331 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1598631
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:2317291
G Khsrp KH-type splicing regulatory protein JBrowse link 9 10,013,795 10,023,670 RGD:1600115
RGD:1624291
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
RGD:1600115
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:1624291
RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590175
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1600115
RGD:1624291
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:1624291
RGD:1600115
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317158
G Wdr35 WD repeat domain 35 JBrowse link 6 34,094,291 34,152,048 RGD:11553926
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
nitric oxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:1600115
RGD:1624291
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:633683
G LOC497963 similar to Nitric oxide synthase, inducible (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) JBrowse link 10 66,282,171 66,313,373 RGD:1600115
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1358520
RGD:13792537
RGD:1624291
RGD:1600115
RGD:8553334
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:1358527
RGD:13792537
RGD:1624291
RGD:1600115
RGD:8656011
RGD:1580262
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:628542
RGD:13792537
RGD:1624291
RGD:1600115
RGD:7794722
G P2rx4 purinergic receptor P2X 4 JBrowse link 12 39,308,022 39,325,673 RGD:1624291
G Rora RAR-related orphan receptor A JBrowse link 8 75,515,886 75,616,477 RGD:1624291
G Slc7a2 solute carrier family 7 member 2 JBrowse link 16 54,459,409 54,513,349 RGD:1624291
G Spr sepiapterin reductase JBrowse link 4 116,912,343 116,916,073 RGD:1624291
octopamine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbh dopamine beta-hydroxylase JBrowse link 3 5,709,236 5,731,895 RGD:13792537
G Moxd1 monooxygenase, DBH-like 1 JBrowse link 1 22,124,498 22,206,565 RGD:13792537
G Moxd2 monooxygenase, DBH-like 2 JBrowse link 4 69,117,477 69,125,972 RGD:13792537
positive regulation of nitric oxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:8548892
G Agxt2 alanine-glyoxylate aminotransferase 2 JBrowse link 2 60,337,667 60,379,144 RGD:1624291
RGD:13792537
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:2313017
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:2313325
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:1624291
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9586000
G Ddah1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 2 251,634,368 251,766,009 RGD:727432
RGD:13792537
RGD:1624291
G Ddah2 dimethylarginine dimethylaminohydrolase 2 JBrowse link 20 5,049,260 5,052,573 RGD:13792537
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:9685181
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:727463
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:1624291
RGD:1600115
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:1600239
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2306941
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:1624291
RGD:1600115
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1600239
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1641934
G Klf2 Kruppel-like factor 2 JBrowse link 16 19,223,087 19,225,037 RGD:1624291
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:1624291
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like JBrowse link 20 3,242,236 3,253,995 RGD:1624291
G LOC103692716 heat shock protein HSP 90-alpha JBrowse link 6 135,044,833 135,050,417 RGD:1600115
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304240
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1600115
RGD:1624291
RGD:13792525
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10041012
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5135054
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:10041069
G Ptx3 pentraxin 3 JBrowse link 2 158,097,843 158,103,653 RGD:1624291
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 JBrowse link 20 1,814,661 1,833,033 RGD:1600115
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:11535100
RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:10042970
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1624291
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1600115
RGD:1624291
G Tlr5 toll-like receptor 5 JBrowse link 13 101,364,784 101,385,764 RGD:1643119
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:2317115
G Ulbp1 UL16 binding protein 1 JBrowse link 1 1,181,301 1,200,526 RGD:1624291
regulation of nitric oxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:634667
G Cd47 Cd47 molecule JBrowse link 11 53,511,485 53,575,754 RGD:1600115
RGD:1624291
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:1624291
G Gchfr GTP cyclohydrolase I feedback regulator JBrowse link 3 110,975,923 110,979,957 RGD:728623
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:13792550
G Nos1ap nitric oxide synthase 1 adaptor protein JBrowse link 13 88,653,123 88,943,976 RGD:8553554
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1624291
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:13792550
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:13792550
serotonin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddc dopa decarboxylase JBrowse link 14 91,905,919 91,996,816 RGD:5129182
G Tph2 tryptophan hydroxylase 2 JBrowse link 7 58,042,279 58,149,220 RGD:1600115
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:11353778
G Tph1 tryptophan hydroxylase 1 JBrowse link 1 102,669,868 102,699,442 RGD:625621

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    cellular process 18179
      cellular metabolic process 10644
        neurotransmitter metabolic process 158
          neurotransmitter biosynthetic process 110
            acetylcholine biosynthetic process + 3
            beta-alanine biosynthetic process + 2
            choline biosynthetic process + 0
            gamma-aminobutyric acid biosynthetic process 3
            glycine biosynthetic process + 6
            histamine biosynthetic process 2
            nitric oxide biosynthetic process + 83
            octopamine biosynthetic process 3
            phenylethylamine biosynthetic process involved in synaptic transmission 0
            serotonin biosynthetic process + 4
            tyramine biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    biological regulation 13446
      regulation of biological quality 4275
        regulation of neurotransmitter levels 412
          neurotransmitter metabolic process 158
            neurotransmitter biosynthetic process 110
              acetylcholine biosynthetic process + 3
              beta-alanine biosynthetic process + 2
              choline biosynthetic process + 0
              gamma-aminobutyric acid biosynthetic process 3
              glycine biosynthetic process + 6
              histamine biosynthetic process 2
              nitric oxide biosynthetic process + 83
              octopamine biosynthetic process 3
              phenylethylamine biosynthetic process involved in synaptic transmission 0
              serotonin biosynthetic process + 4
              tyramine biosynthetic process 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.