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ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-6 biosynthetic process
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Accession:GO:0042226 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of interleukin-6.
Synonyms:exact_synonym: IL-6 biosynthesis;   IL-6 biosynthetic process;   interleukin-6 anabolism;   interleukin-6 biosynthesis;   interleukin-6 formation;   interleukin-6 synthesis


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interleukin-6 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il19 interleukin 19 JBrowse link 13 47,663,592 47,677,869 RGD:1624291
RGD:1600115
negative regulation of interleukin-6 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624291
RGD:1600115
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:1624291
RGD:1600115
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:1624291
RGD:1600115
G Muc16 mucin 16, cell surface associated JBrowse link 8 18,438,838 18,639,777 RGD:1624291
G Nlrp12 NLR family, pyrin domain containing 12 JBrowse link 1 64,506,750 64,543,908 RGD:1624291
RGD:13792537
G Prg4 proteoglycan 4 JBrowse link 13 67,672,588 67,688,902 RGD:1624291
positive regulation of interleukin-6 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1600115
RGD:1624291
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1600115
RGD:1624291
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
RGD:1600115
G Ereg epiregulin JBrowse link 14 18,577,620 18,591,395 RGD:1624291
RGD:1600115
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13513988
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
RGD:1600115
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G LOC103694380 tumor necrosis factor-like JBrowse link 20 4,855,792 4,858,447 RGD:13800534
G Ptafr platelet-activating factor receptor JBrowse link 5 150,746,284 150,775,675 RGD:10043184
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:13800534
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:1624291
RGD:1600115
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:13800534
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
RGD:1600115
G Tyrobp Tyro protein tyrosine kinase binding protein JBrowse link 1 88,875,370 88,879,305 RGD:1624291
regulation of interleukin-6 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Card9 caspase recruitment domain family, member 9 JBrowse link 3 3,798,346 3,806,841 RGD:1624291
RGD:1600115
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Il17f interleukin 17F JBrowse link 9 26,885,702 26,897,219 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    multicellular organismal process 8585
      cytokine production 783
        cytokine biosynthetic process 116
          interleukin-6 biosynthetic process 28
            negative regulation of interleukin-6 biosynthetic process 7
            positive regulation of interleukin-6 biosynthetic process 17
            regulation of interleukin-6 biosynthetic process + 27
Path 2
Term Annotations click to browse term
  biological_process 18008
    metabolic process 10729
      organic substance metabolic process 10177
        macromolecule metabolic process 8720
          protein metabolic process 5543
            cytokine metabolic process 120
              cytokine biosynthetic process 116
                interleukin-6 biosynthetic process 28
                  negative regulation of interleukin-6 biosynthetic process 7
                  positive regulation of interleukin-6 biosynthetic process 17
                  regulation of interleukin-6 biosynthetic process + 27
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.