ONTOLOGY REPORT - ANNOTATIONS


Term:interleukin-8 biosynthetic process
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Accession:GO:0042228 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of interleukin-8.
Synonyms:exact_synonym: IL-8 biosynthesis;   IL-8 biosynthetic process;   interleukin-8 anabolism;   interleukin-8 biosynthesis;   interleukin-8 formation;   interleukin-8 synthesis


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interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 4 85,123,965 85,175,206 RGD:1624291
RGD:1600115
negative regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:1624291
RGD:1600115
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
RGD:1600115
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
RGD:1600115
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:8553940
positive regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa2 apolipoprotein A2 JBrowse link 13 89,596,872 89,598,805 RGD:1624291
RGD:1600115
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
RGD:1600115
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
RGD:1600115
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 JBrowse link 3 72,395,194 72,401,254 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1624291
RGD:13792537
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1624291
RGD:13792537
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:13792537
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
regulation of interleukin-8 biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il17f interleukin 17F JBrowse link 9 26,885,702 26,897,219 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    multicellular organismal process 8539
      cytokine production 775
        cytokine biosynthetic process 114
          interleukin-8 biosynthetic process 14
            negative regulation of interleukin-8 biosynthetic process 4
            positive regulation of interleukin-8 biosynthetic process 9
            regulation of interleukin-8 biosynthetic process + 13
Path 2
Term Annotations click to browse term
  biological_process 17926
    metabolic process 10677
      organic substance metabolic process 10127
        macromolecule metabolic process 8686
          protein metabolic process 5526
            cytokine metabolic process 118
              cytokine biosynthetic process 114
                interleukin-8 biosynthetic process 14
                  negative regulation of interleukin-8 biosynthetic process 4
                  positive regulation of interleukin-8 biosynthetic process 9
                  regulation of interleukin-8 biosynthetic process + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.