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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of natural killer cell mediated cytotoxicity
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Accession:GO:0042269 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity.
Synonyms:exact_synonym: regulation of NK cell mediated cell death;   regulation of NK cell mediated cell killing;   regulation of natural killer cell mediated cell death;   regulation of natural killer cell mediated cell killing
 related_synonym: regulation of NK cell mediated cytolysis;   regulation of NK cell mediated cytotoxicity;   regulation of natural killer cell mediated cytolysis


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regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LEP leptin JBrowse link 18 20,106,867 20,124,071 RGD:14298760
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLEC12B C-type lectin domain family 12 member B JBrowse link 5 61,908,463 61,915,328 RGD:14298760
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HAVCR2 hepatitis A virus cellular receptor 2 JBrowse link 16 66,138,157 66,160,568 RGD:14298760
positive regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LAMP1 lysosomal associated membrane protein 1 JBrowse link 11 78,600,818 78,617,587 RGD:14298760
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL18RAP interleukin 18 receptor accessory protein JBrowse link 3 51,762,111 51,794,552 RGD:14298760
G IL21 interleukin 21 JBrowse link 8 101,532,742 101,540,712 RGD:14298760
G KLRK1 killer cell lectin like receptor K1 JBrowse link 5 61,646,691 61,655,386 RGD:14298760
G LAG3 lymphocyte activating 3 JBrowse link 5 63,929,669 63,935,054 RGD:14298760
G LOC100519314 natural killer cells antigen CD94 JBrowse link 5 61,724,744 61,736,667 RGD:14298760
G NCR3 natural cytotoxicity triggering receptor 3 JBrowse link 7 23,713,333 23,716,988 RGD:14298760
G RASGRP1 RAS guanyl releasing protein 1 JBrowse link 1 132,702,495 132,786,536 RGD:14298760
G SH2D1A SH2 domain containing 1A JBrowse link X 101,824,602 101,847,265 RGD:14298760
G SLAMF6 SLAM family member 6 JBrowse link 4 89,980,592 90,004,222 RGD:14298760
G STAT5B signal transducer and activator of transcription 5B JBrowse link 12 20,498,103 20,574,365 RGD:14298760
G VAV1 vav guanine nucleotide exchange factor 1 JBrowse link 2 72,327,433 72,391,649 RGD:14298760
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD226 CD226 molecule JBrowse link 1 152,872,878 152,977,162 RGD:14298760
G CRTAM cytotoxic and regulatory T cell molecule JBrowse link 9 49,782,166 49,811,314 RGD:14298760
G IL12A interleukin 12A JBrowse link 13 99,733,394 99,741,078 RGD:14298760
G IL12B interleukin 12B JBrowse link 16 64,143,268 64,158,929 RGD:14298760
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 6 51,317,386 51,358,665 RGD:14298760
G PVR PVR cell adhesion molecule JBrowse link 6 51,161,320 51,178,464 RGD:14298760
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CADM1 cell adhesion molecule 1 JBrowse link 9 42,644,487 42,984,934 RGD:14298760
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 6 51,317,386 51,358,665 RGD:14298760
G PVR PVR cell adhesion molecule JBrowse link 6 51,161,320 51,178,464 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15166
    regulation of biological process 9651
      regulation of cellular process 9251
        regulation of cell killing 63
          regulation of leukocyte mediated cytotoxicity 47
            regulation of natural killer cell mediated cytotoxicity 22
              negative regulation of natural killer cell mediated cytotoxicity + 2
              positive regulation of natural killer cell mediated cytotoxicity + 19
              regulation of natural killer cell degranulation + 1
              regulation of natural killer cell mediated cytotoxicity directed against tumor cell target + 7
Path 2
Term Annotations click to browse term
  biological_process 15166
    response to stimulus 7105
      response to biotic stimulus 818
        response to external biotic stimulus 795
          response to other organism 792
            defense response to other organism 561
              innate immune response 382
                natural killer cell mediated immunity 33
                  regulation of natural killer cell mediated immunity 24
                    regulation of natural killer cell mediated cytotoxicity 22
                      negative regulation of natural killer cell mediated cytotoxicity + 2
                      positive regulation of natural killer cell mediated cytotoxicity + 19
                      regulation of natural killer cell degranulation + 1
                      regulation of natural killer cell mediated cytotoxicity directed against tumor cell target + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.