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ONTOLOGY REPORT - ANNOTATIONS


Term:vasoconstriction
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Accession:GO:0042310 term browser browse the term
Definition:A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure.
Synonyms:exact_synonym: negative regulation of blood vessel size
 alt_id: GO:0045908
 xref: Wikipedia:Vasoconstriction


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vasoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IMP RGD PMID:20204775 RGD:2325222 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Agt angiotensinogen IDA RGD PMID:20955746 RGD:5129197 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:20955746 RGD:5129197 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Avp arginine vasopressin IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bdkrb2 bradykinin receptor B2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Cav1 caveolin 1 IEA
ISO
GO_REF:0000107
MGI:2180364 (MGI:3707284|PMID:17098833)
Ensembl
RGD
PMID:17098833 GO_REF:0000107, MGI:3707284 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Edn1 endothelin 1 IDA
ISO
(PMID:11410113), (PMID:2649896) RGD PMID:2649896, PMID:11410113, PMID:19628632 RGD:4892557 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 ISO (PMID:2649896), (PMID:8982507) RGD PMID:2649896, PMID:8982507 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Edn3 endothelin 3 ISO
IEA
(PMID:2649896), (PMID:8982507)
GO_REF:0000043
RGD
UniProt
PMID:2649896, PMID:8982507 GO_REF:0000043 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednra endothelin receptor type A IMP
ISO
IEA
(MGI:1314982|PMID:9826706)
GO_REF:0000002
(PMID:8982507)
RGD
InterPro
PMID:8982507, PMID:9826706, PMID:14678950 GO_REF:0000002, MGI:1314982, RGD:1581832 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B IMP
ISO
(PMID:8982507) RGD PMID:8982507, PMID:14678950 RGD:1581832 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15625277)
Ensembl
UniProt
RGD
PMID:15625277 GO_REF:0000024, GO_REF:0000107 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G LOC103694905 5-hydroxytryptamine receptor 7 IEA GO_REF:0000002 InterPro GO_REF:0000002
G Slc6a4 solute carrier family 6 member 4 IMP RGD PMID:14605793 RGD:4889444 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO (MGI:1342129|PMID:10425188) RGD PMID:10425188 MGI:1342129 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO MGI:2182739 (MGI:3694178|PMID:15998684) RGD PMID:15998684 MGI:3694178 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Rhoa ras homolog family member A ISO (MGI:5638847|PMID:24335996) RGD PMID:24335996 MGI:5638847 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
artery smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:21076237 RGD:5129195 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 ISO MGI:3521669 (MGI:4867605|PMID:20852044) RGD PMID:20852044 MGI:4867605 NCBI chr19:11,385,921...11,421,523
Ensembl chr19:11,386,024...11,421,498
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G IMP RGD PMID:18759855 RGD:2308879 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cd38 CD38 molecule IMP RGD PMID:21431168 RGD:13506923 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Edn1 endothelin 1 ISO
IDA
(PMID:8982507) RGD PMID:8982507, PMID:7586220 RGD:8662314 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 ISO
IEA
(PMID:8982507)
GO_REF:0000107
RGD
Ensembl
PMID:8982507 GO_REF:0000107 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Edn3 endothelin 3 NOT ISO (PMID:8982507) RGD PMID:8982507 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednra endothelin receptor type A ISO
IEA
(PMID:8982507)
GO_REF:0000107
RGD
Ensembl
PMID:8982507 GO_REF:0000107 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Grip2 glutamate receptor interacting protein 2 ISO MGI:3035933 (MGI:5609934|PMID:23117660) RGD PMID:23117660 MGI:5609934 NCBI chr 4:123,585,184...123,636,040
Ensembl chr 4:123,586,231...123,636,040
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:14752059 RGD:7257678 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Mkks McKusick-Kaufman syndrome ISO MGI:3526444 (MGI:4867605|PMID:20852044) RGD PMID:20852044 MGI:4867605 NCBI chr 3:129,866,542...129,885,213
Ensembl chr 3:129,866,545...129,884,810
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta IEA
ISO
GO_REF:0000107
MGI:2179831 (MGI:4356406|PMID:19553501)
Ensembl
RGD
PMID:19553501 GO_REF:0000107, MGI:4356406 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:19088082 RGD:10042965 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
negative regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap42 Rho GTPase activating protein 42 ISO MGI:3871380 (MGI:5638847|PMID:24335996) RGD PMID:24335996 MGI:5638847 NCBI chr 8:7,210,999...7,446,215
Ensembl chr 8:7,213,822...7,426,611
JBrowse link
G Dock4 dedicator of cytokinesis 4 ISO (PMID:22158624) RGD PMID:22158624 NCBI chr 6:60,374,839...60,782,648
Ensembl chr 6:60,566,196...60,782,556
JBrowse link
G Dock5 dedicator of cytokinesis 5 ISO (PMID:22158624) RGD PMID:22158624 NCBI chr15:44,449,108...44,627,774
Ensembl chr15:44,453,308...44,627,765
JBrowse link
negative regulation of vasoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO (PMID:11410113) RGD PMID:11410113 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Ahr aryl hydrocarbon receptor ISO (MGI:3760685|PMID:14644620) RGD PMID:14644620 MGI:3760685 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Apln apelin IMP RGD PMID:17318790 RGD:1626185 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO (MGI:3799581|PMID:18552156) RGD PMID:18552156 MGI:3799581 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IDA RGD PMID:19201996 RGD:4891967 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Dusp5 dual specificity phosphatase 5 IMP RGD PMID:25397684 RGD:13446412 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:21106323 RGD:5147878 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IMP regulates cerebral vasospasm following subarachnoid hemorrhage RGD PMID:15381648 RGD:1626660 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Lep leptin IDA RGD PMID:20978518 RGD:5128573 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Mmp2 matrix metallopeptidase 2 IDA RGD PMID:19482300 RGD:2325737 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Nos1 nitric oxide synthase 1 IMP RGD PMID:23640592 RGD:7257607 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A ISO MGI:2387663 (MGI:2182494|PMID:12093905) RGD PMID:12093905 MGI:2182494 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1d adrenoceptor alpha 1D ISO (MGI:2656483|PMID:12595294) RGD PMID:12595294 MGI:2656483 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Drd5 dopamine receptor D5 IEA
ISO
GO_REF:0000107
MGI:3528074 (MGI:3527993|PMID:12486173)
Ensembl
RGD
PMID:12486173 GO_REF:0000107, MGI:3527993 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3 IMP RGD PMID:8428203 RGD:2303387 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Rhoa ras homolog family member A ISO (MGI:5638847|PMID:24335996) RGD PMID:24335996 MGI:5638847 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
positive regulation of vasoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase IMP RGD PMID:17615370 RGD:8693596 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Add3 adducin 3 IMP RGD PMID:27927653 RGD:13446409 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Adra1a adrenoceptor alpha 1A IDA
IBA
IMP
PMID:21873635
PMID:19011682
RGD
GO_Central
BHF-UCL
PMID:15877108, PMID:21873635, PMID:19011682, PMID:22040923 RGD:1625777, RGD:13792537, RGD:5688340, RGD:5688308 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1b adrenoceptor alpha 1B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adra1d adrenoceptor alpha 1D IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:17199872, PMID:21873635 RGD:5688350, RGD:13792537 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Adra2c adrenoceptor alpha 2C IMP RGD PMID:20862454 RGD:6893567 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IMP RGD PMID:21532183 RGD:5509096 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:16331105 RGD:1626151 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Avp arginine vasopressin IMP RGD PMID:18483147 RGD:2301932 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:17428891, PMID:21873635 RGD:2300345, RGD:13792537 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Avpr1b arginine vasopressin receptor 1B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Avpr2 arginine vasopressin receptor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Casr calcium-sensing receptor IMP RGD PMID:22098336 RGD:7205678 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cav1 caveolin 1 IMP
ISO
IEA
MGI:2180364 (MGI:2176684|PMID:11884617)
GO_REF:0000107
RGD
Ensembl
PMID:11884617, PMID:21098487 GO_REF:0000107, MGI:2176684, RGD:6849297 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cd38 CD38 molecule IMP RGD PMID:18524860 RGD:2307237 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 IMP RGD PMID:9316844 RGD:2303391 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 IMP RGD PMID:16445567, PMID:16331105 RGD:2316238, RGD:1626151 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Dbh dopamine beta-hydroxylase IEA
ISO
GO_REF:0000107
MGI:1857556 (MGI:87391|PMID:9139828)
Ensembl
RGD
PMID:9139828 GO_REF:0000107, MGI:87391 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:22966991 RGD:7204494 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G F2r coagulation factor II (thrombin) receptor IDA
ISO
IEA
(MGI:5315674|PMID:21859963)
GO_REF:0000107
RGD
Ensembl
PMID:21859963, PMID:12644441 GO_REF:0000107, MGI:5315674, RGD:1582293 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO (PMID:24506284) RGD PMID:24506284 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Fga fibrinogen alpha chain ISO
IEA
(PMID:15739255)
GO_REF:0000107
RGD
Ensembl
PMID:15739255 GO_REF:0000107 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain ISO (PMID:15739255) RGD PMID:15739255 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain ISO (PMID:15739255) RGD PMID:15739255 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:21414209 RGD:7207411 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 IMP RGD PMID:21414209 RGD:7207411 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:28882814 RGD:13506839 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Hrh1 histamine receptor H 1 IMP
IEA
GO_REF:0000002 InterPro PMID:17169617 GO_REF:0000002, RGD:1642309 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Hrh2 histamine receptor H 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:16527989 RGD:1582161 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:15118345 RGD:1625008 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Icam1 intercellular adhesion molecule 1 IMP RGD PMID:12296653 RGD:4145431 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Klk1c9 kallikrein 1-related peptidase C9 IDA RGD PMID:1900513 RGD:1302426 NCBI chr 1:100,086,520...100,090,406
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ISO (PMID:24506284) RGD PMID:24506284 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:9802404 RGD:1642323 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Oxtr oxytocin receptor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116
JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:19542492 RGD:2314461 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:1667284, PMID:8581269 RGD:10043146, RGD:10043165 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10747002 RGD:10043337 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:18456673 RGD:2300248 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18456673 RGD:2300248 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rhoa ras homolog family member A IEP RGD PMID:17468135 RGD:1642958 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Shc1 SHC adaptor protein 1 IMP RGD PMID:16242150 RGD:1643184 NCBI chr 2:188,745,503...188,757,066
Ensembl chr 2:188,745,503...188,757,066
JBrowse link
G Smtnl1 smoothelin-like 1 ISO
IBA
MGI:3796616 (MGI:3796498|PMID:18310078), (MGI:4844228|PMID:20634291)
PMID:21873635
RGD PMID:18310078, PMID:20634291, PMID:21873635 MGI:3796498, MGI:4844228, RGD:13792537 NCBI chr 3:72,207,150...72,219,209
Ensembl chr 3:72,207,113...72,219,246
JBrowse link
G Smtnl2 smoothelin-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:58,951,845...58,973,020
Ensembl chr10:58,951,842...58,973,020
JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:18602450 RGD:2304265 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tbxa2r thromboxane A2 receptor IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:16905600, PMID:21873635, PMID:10513923 RGD:1601433, RGD:13792537, RGD:11059603 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977
JBrowse link
G Tbxas1 thromboxane A synthase 1 IMP RGD PMID:9370383 RGD:1601472 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:20610768, PMID:15472118 RGD:9999443, RGD:10003027 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:15554454 RGD:2306845 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2b adrenoceptor alpha 2B IMP RGD PMID:18054907 RGD:2313547 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 ISS
ISO
GO_REF:0000024
(MGI:6282934|PMID:24805951)
UniProt
RGD
PMID:24805951 GO_REF:0000024, MGI:6282934 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IMP inhibition decreases both calcium-stimulated and unstimulated myogenic tone in middle cerebral arteries (p<0.001) RGD PMID:10198244 RGD:2293329 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G P2rx1 purinergic receptor P2X 1 ISO MGI:2181608 (MGI:3694186|PMID:16920810) RGD PMID:16920810 MGI:3694186 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G Zdhhc21 zinc finger DHHC-type palmitoyltransferase 21 ISO (MGI:5921050|PMID:26715683) RGD PMID:26715683 MGI:5921050 NCBI chr 5:100,924,621...100,983,412
Ensembl chr 5:100,924,622...100,977,902
JBrowse link
regulation of vasoconstriction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1b adrenoceptor alpha 1B IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adra2a adrenoceptor alpha 2A IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO (PMID:15117835) RGD PMID:15117835 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr1b angiotensin II receptor, type 1b IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:105,149,020...105,224,335
Ensembl chr 2:105,149,020...105,224,295
JBrowse link
G Asic2 acid sensing ion channel subunit 2 IEA
ISO
GO_REF:0000107
MGI:2180111 (MGI:3794223|PMID:18296560)
Ensembl
RGD
PMID:18296560 GO_REF:0000107, MGI:3794223 NCBI chr10:68,247,800...69,347,223
Ensembl chr10:68,248,655...68,517,564
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 ISO MGI:2451291|MGI:98469 (MGI:3525892|PMID:14627611) RGD PMID:14627611 MGI:3525892 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO MGI:2389040|MGI:2674119 (MGI:3663939|PMID:14609949) RGD PMID:14609949 MGI:3663939 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Drd1 dopamine receptor D1 IMP RGD PMID:15778266 RGD:7175070 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Edn1 endothelin 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Edn3 endothelin 3 TAS
IEA
GO_REF:0000002 InterPro PMID:12184995 GO_REF:0000002, RGD:1299957 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 ISO MGI:2384510 (MGI:2138011|PMID:11481235) RGD PMID:11481235 MGI:2138011 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G P2rx1 purinergic receptor P2X 1 ISO MGI:2181608 (MGI:3699669|PMID:14679185) RGD PMID:14679185 MGI:3699669 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G Per2 period circadian regulator 2 ISS
ISO
GO_REF:0000024
(MGI:3794791|PMID:17404161)
UniProt
RGD
PMID:17404161 GO_REF:0000024, MGI:3794791 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Prkcq protein kinase C, theta IEP RGD PMID:16951045 RGD:1625607 NCBI chr17:70,971,915...71,105,286
Ensembl chr17:70,971,915...71,105,286
JBrowse link
G Tbxa2r thromboxane A2 receptor ISO MGI:88106 (MGI:3525892|PMID:14627611) RGD PMID:14627611 MGI:3525892 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977
JBrowse link
regulation of vasoconstriction by circulating norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snta1 syntrophin, alpha 1 ISO MGI:2179769 (MGI:3691879|PMID:12600881) RGD PMID:12600881 MGI:3691879 NCBI chr 3:149,874,023...149,905,980
Ensembl chr 3:149,874,030...149,905,944
JBrowse link
regulation of vein smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:31125290 RGD:14696717 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle IEA
ISO
GO_REF:0000107
MGI:3665248 (MGI:3665239|PMID:11053242)
Ensembl
RGD
PMID:11053242 GO_REF:0000107, MGI:3665239 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actg2 actin gamma 2, smooth muscle IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Comp cartilage oligomeric matrix protein IEA
ISO
GO_REF:0000107
MGI:2180787 (MGI:5824640|PMID:27498005)
Ensembl
RGD
PMID:27498005 GO_REF:0000107, MGI:5824640 NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070
JBrowse link
G Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 IMP RGD PMID:18348285 RGD:2314690 NCBI chr 2:244,258,550...244,370,983
Ensembl chr 2:244,258,550...244,370,983
JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO (MGI:1927695|PMID:10967099) RGD PMID:10967099 MGI:1927695 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1b adrenoceptor alpha 1B ISO MGI:2148638 (MGI:1098078|PMID:9326654) RGD PMID:9326654 MGI:1098078 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Manf mesencephalic astrocyte-derived neurotrophic factor ISO (MGI:3820809|PMID:18718866) RGD PMID:18718866 MGI:3820809 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
vein smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO
IBA
(PMID:9422810)
PMID:21873635
RGD PMID:9422810, PMID:21873635 RGD:13792537 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:8982507), (PMID:9422810)
Ensembl
RGD
PMID:8982507, PMID:9422810, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Edn3 endothelin 3 ISO
IBA
(PMID:8982507)
PMID:21873635
RGD PMID:8982507, PMID:21873635 RGD:13792537 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednrb endothelin receptor type B ISO (PMID:8982507) RGD PMID:8982507 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    multicellular organismal process 9045
      system process 3445
        circulatory system process 557
          vascular process in circulatory system 223
            blood vessel diameter maintenance 162
              vasoconstriction 109
                angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure 3
                negative regulation of vasoconstriction + 14
                norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure 3
                positive regulation of vasoconstriction + 50
                regulation of vasoconstriction + 84
                vascular associated smooth muscle contraction + 30
                vasoconstriction by vasopressin involved in systemic arterial blood pressure control 0
                vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure 1
                vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure + 0
                vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure 1
Path 2
Term Annotations click to browse term
  biological_process 20030
    biological regulation 13774
      regulation of biological quality 4273
        regulation of anatomical structure size 597
          regulation of tube size 163
            regulation of tube diameter 162
              blood vessel diameter maintenance 162
                vasoconstriction 109
                  angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure 3
                  negative regulation of vasoconstriction + 14
                  norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure 3
                  positive regulation of vasoconstriction + 50
                  regulation of vasoconstriction + 84
                  vascular associated smooth muscle contraction + 30
                  vasoconstriction by vasopressin involved in systemic arterial blood pressure control 0
                  vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure 1
                  vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure + 0
                  vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.