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ONTOLOGY REPORT - ANNOTATIONS


Term:vasodilation
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Accession:GO:0042311 term browser browse the term
Definition:An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
Synonyms:exact_synonym: positive regulation of blood vessel size;   vasodilatation
 xref: Wikipedia:Vasodilation


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vasodilation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IMP AMPA induced dilation of pial artery
in renal medulla
RGD PMID:16601261, PMID:10070140 RGD:1625442, RGD:628573 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Agt angiotensinogen IDA RGD PMID:21056585 RGD:5129196 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO (PMID:15117835), (PMID:17159079) RGD PMID:15117835, PMID:17159079 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Alb albumin NAS RGD PMID:11983891 RGD:708312 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Apoe apolipoprotein E ISO MGI:2137814 (MGI:1314982|PMID:9826706) RGD PMID:9826706 MGI:1314982 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Atg5 autophagy related 5 IEA
ISO
GO_REF:0000107
MGI:3050453|MGI:3663625 (MGI:3711608|PMID:17450150)
Ensembl
RGD
PMID:17450150 GO_REF:0000107, MGI:3711608 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 ISO MGI:3521669 (MGI:4867605|PMID:20852044) RGD PMID:20852044 MGI:4867605 NCBI chr19:11,385,921...11,421,523
Ensembl chr19:11,386,024...11,421,498
JBrowse link
G Bdkrb2 bradykinin receptor B2 IEA
ISO
GO_REF:0000107
MGI:1857135 (MGI:3691970|PMID:11282893)
Ensembl
RGD
PMID:11282893 GO_REF:0000107, MGI:3691970 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Calca calcitonin-related polypeptide alpha IDA RGD PMID:12903912 RGD:1598597 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Casr calcium-sensing receptor IMP RGD PMID:15084499 RGD:1358486 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cftr CF transmembrane conductance regulator IMP RGD PMID:16859673 RGD:1599593 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 ISO (PMID:14718356) RGD PMID:14718356 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Drd1 dopamine receptor D1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:14678950 RGD:1581832 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Ext1 exostosin glycosyltransferase 1 ISO MGI:108050 (MGI:6343289|PMID:31365577) RGD PMID:31365577 MGI:6343289 NCBI chr 7:92,605,008...92,881,392
Ensembl chr 7:92,605,728...92,882,068
JBrowse link
G Ext2 exostosin glycosyltransferase 2 ISO MGI:894663 (MGI:6343289|PMID:31365577) RGD PMID:31365577 MGI:6343289 NCBI chr 3:82,602,784...82,734,557
Ensembl chr 3:82,602,785...82,734,533
JBrowse link
G Gch1 GTP cyclohydrolase 1 IMP RGD PMID:12855421 RGD:1601283 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gpx1 glutathione peroxidase 1 IEA
ISO
GO_REF:0000107
MGI:2158814 (MGI:2177968|PMID:11893559), (MGI:3654264|PMID:12196344)
Ensembl
RGD
PMID:11893559, PMID:12196344 GO_REF:0000107, MGI:2177968, MGI:3654264 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Itga1 integrin subunit alpha 1 IMP flow-mediated dilation of mesenteric resistance arteries RGD PMID:18245559 RGD:2302134 NCBI chr 2:47,127,403...47,281,387
Ensembl chr 2:47,127,219...47,281,421
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 ISO MGI:3050114 (MGI:3695011|PMID:15867178) RGD PMID:15867178 MGI:3695011 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Kng1 kininogen 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:81,421,672...81,444,466
Ensembl chr11:81,421,676...81,444,621
JBrowse link
G Kng2 kininogen 2 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Kng2l1 kininogen 2-like 1 IEA GO_REF:0000043 UniProt GO_REF:0000043
G Mir29a microRNA 29a IMP RGD PMID:29374012 RGD:13702880 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir29b1 microRNA 29b-1 IMP RGD PMID:29374012 RGD:13702880 NCBI chr 4:58,344,310...58,344,390
Ensembl chr 4:58,344,310...58,344,390
JBrowse link
G Mkks McKusick-Kaufman syndrome ISO MGI:3526444 (MGI:4867605|PMID:20852044) RGD PMID:20852044 MGI:4867605 NCBI chr 3:129,866,542...129,885,213
Ensembl chr 3:129,866,545...129,884,810
JBrowse link
G Nos1 nitric oxide synthase 1 IEA
ISO
GO_REF:0000107
(PMID:18048451), (PMID:18391107)
Ensembl
RGD
PMID:18048451, PMID:18391107 GO_REF:0000107 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nppa natriuretic peptide A IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G P2rx4 purinergic receptor P2X 4 ISO MGI:3612982 (MGI:3612001|PMID:16327800) RGD PMID:16327800 MGI:3612001 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Pde5a phosphodiesterase 5A IEP RGD PMID:16545481 RGD:1582534 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ISO MGI:3620600|MGI:3620601 (MGI:3618677|PMID:16467571) RGD PMID:16467571 MGI:3618677 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
G Sod2 superoxide dismutase 2 ISO MGI:1857480 (MGI:3577668|PMID:15637112) RGD PMID:15637112 MGI:3577668 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:16284227 RGD:1580206 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sod2 superoxide dismutase 2 ISO MGI:1857129|MGI:1857480 (MGI:3765405|PMID:16873728) RGD PMID:16873728 MGI:3765405 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 ISO MGI:1857123 (MGI:1342129|PMID:10425188) RGD PMID:10425188 MGI:1342129 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO MGI:2182739 (MGI:3694178|PMID:15998684) RGD PMID:15998684 MGI:3694178 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha ISO MGI:2445489 (MGI:2445452|PMID:11717154) RGD PMID:11717154 MGI:2445452 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IEA
ISO
IBA
GO_REF:0000107
MGI:1857120|MGI:87938 (MGI:1338641|PMID:10358009), (MGI:3608195|PMID:11641423)
PMID:21873635
Ensembl
RGD
PMID:10358009, PMID:11641423, PMID:21873635 GO_REF:0000107, MGI:1338641, MGI:3608195, RGD:13792537 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 IEA
ISO
IBA
GO_REF:0000107
MGI:1859675|MGI:87937 (MGI:1338641|PMID:10358009), (MGI:3608195|PMID:11641423)
PMID:21873635
Ensembl
RGD
PMID:10358009, PMID:11641423, PMID:21873635 GO_REF:0000107, MGI:1338641, MGI:3608195, RGD:13792537 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 IBA
ISO
PMID:21873635
(MGI:1338641|PMID:10358009)
RGD PMID:10358009, PMID:21873635 MGI:1338641, RGD:13792537 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
relaxation of vascular associated smooth muscle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IMP RGD PMID:19443947 RGD:2317917 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2b adenosine A2B receptor IEA
ISO
GO_REF:0000107
MGI:3773754 (MGI:3794903|PMID:18340377)
Ensembl
RGD
PMID:18340377 GO_REF:0000107, MGI:3794903 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 IEA
ISO
GO_REF:0000107
MGI:3640802 (MGI:3640061|PMID:16614755)
Ensembl
RGD
PMID:16614755 GO_REF:0000107, MGI:3640061 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 ISO MGI:3525059 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:175,681,960...175,804,737
Ensembl chr 1:175,681,960...175,796,040
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 ISO
IBA
(PMID:25139746)
MGI:3050114 (MGI:3695011|PMID:15867178)
PMID:21873635
RGD PMID:15867178, PMID:25139746, PMID:21873635 MGI:3695011, RGD:13792537 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 ISO MGI:2181586 (MGI:3512693|PMID:15483626) RGD PMID:15483626 MGI:3512693 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO (MGI:2682081|PMID:14608379) RGD PMID:14608379 MGI:2682081 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Sod1 superoxide dismutase 1 ISS
ISO
GO_REF:0000024
MGI:1857873 (MGI:2682495|PMID:14679182), (MGI:3625573|PMID:12433839)
UniProt
RGD
PMID:12433839, PMID:14679182 GO_REF:0000024, MGI:2682495, MGI:3625573 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO (PMID:25139746) RGD PMID:25139746 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    multicellular organismal process 9047
      system process 3456
        circulatory system process 579
          vascular process in circulatory system 248
            blood vessel diameter maintenance 188
              positive regulation of blood vessel diameter 85
                vasodilation 45
                  acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure 1
                  angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure 2
                  artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure 1
                  epinephrine-mediated vasodilation 0
                  norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure 3
                  norepinephrine-mediated vasodilation 0
                  relaxation of vascular associated smooth muscle 9
                  vasodilation in other organism 0
                  vasodilation involved in acute inflammatory response 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological quality 4280
        regulation of anatomical structure size 621
          regulation of tube size 189
            regulation of tube diameter 188
              blood vessel diameter maintenance 188
                positive regulation of blood vessel diameter 85
                  vasodilation 45
                    acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure 1
                    angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure 2
                    artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure 1
                    epinephrine-mediated vasodilation 0
                    norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure 3
                    norepinephrine-mediated vasodilation 0
                    relaxation of vascular associated smooth muscle 9
                    vasodilation in other organism 0
                    vasodilation involved in acute inflammatory response 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.