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ONTOLOGY REPORT - ANNOTATIONS


Term:keratan sulfate catabolic process
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Accession:GO:0042340 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
Synonyms:exact_synonym: keratan sulfate breakdown;   keratan sulfate catabolism;   keratan sulfate degradation;   keratan sulphate catabolic process;   keratan sulphate catabolism


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keratan sulfate catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAN aggrecan TAS Reactome Reactome:R-HSA-2022857 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,354
Ensembl chr15:88,803,436...88,875,354
JBrowse link
G FMOD fibromodulin TAS Reactome Reactome:R-HSA-2022857 NCBI chr 1:203,340,628...203,351,122
Ensembl chr 1:203,340,628...203,351,758
JBrowse link
G GALNS galactosamine (N-acetyl)-6-sulfatase TAS Reactome Reactome:R-HSA-2022857 NCBI chr16:88,813,734...88,856,966
Ensembl chr16:88,813,734...88,856,970
JBrowse link
G GLB1 galactosidase beta 1 TAS Reactome Reactome:R-HSA-2022857 NCBI chr 3:32,996,617...33,097,146
Ensembl chr 3:32,996,609...33,097,202
JBrowse link
G GNS glucosamine (N-acetyl)-6-sulfatase TAS Reactome Reactome:R-HSA-2022857 NCBI chr12:64,713,449...64,759,406
Ensembl chr12:64,713,445...64,759,431
JBrowse link
G HEXA hexosaminidase subunit alpha TAS Reactome Reactome:R-HSA-2022857 NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,919...72,376,476
Ensembl chr15:72,340,919...72,376,476
JBrowse link
G HEXB hexosaminidase subunit beta TAS Reactome Reactome:R-HSA-2022857 NCBI chr 5:74,640,023...74,721,288
Ensembl chr 5:74,640,023...74,722,647
JBrowse link
G KERA keratocan TAS Reactome Reactome:R-HSA-2022857 NCBI chr12:91,050,491...91,058,024
Ensembl chr12:91,050,491...91,058,024
Ensembl chr12:91,050,491...91,058,024
JBrowse link
G LUM lumican TAS Reactome Reactome:R-HSA-2022857 NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494
JBrowse link
G OGN osteoglycin TAS Reactome Reactome:R-HSA-2022857 NCBI chr 9:92,383,268...92,404,699
Ensembl chr 9:92,383,268...92,404,696
JBrowse link
G OMD osteomodulin TAS Reactome Reactome:R-HSA-2022857 NCBI chr 9:92,412,380...92,424,471
Ensembl chr 9:92,414,245...92,424,461
JBrowse link
G PRELP proline and arginine rich end leucine rich repeat protein TAS Reactome Reactome:R-HSA-2022857 NCBI chr 1:203,475,806...203,491,352
Ensembl chr 1:203,475,806...203,491,352
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18673
    metabolic process 12182
      cellular metabolic process 11132
        sulfur compound metabolic process 397
          sulfur compound catabolic process 55
            keratan sulfate catabolic process 12
Path 2
Term Annotations click to browse term
  biological_process 18673
    metabolic process 12182
      organic substance metabolic process 11603
        macromolecule metabolic process 10026
          aminoglycan metabolic process 179
            glycosaminoglycan metabolic process 165
              mucopolysaccharide metabolic process 123
                keratan sulfate metabolic process 33
                  keratan sulfate catabolic process 12
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