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ONTOLOGY REPORT - ANNOTATIONS


Term:vitamin D metabolic process
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Accession:GO:0042359 term browser browse the term
Definition:The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
Synonyms:exact_synonym: vitamin D metabolism
 narrow_synonym: calciferol metabolic process;   calciferol metabolism;   cholecalciferol metabolic process;   cholecalciferol metabolism;   ergocalciferol metabolic process;   ergocalciferol metabolism


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vitamin D metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calb1 calbindin 1 JBrowse link 5 29,538,380 29,562,774 RGD:68751
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 JBrowse link 3 168,097,484 168,111,920 RGD:1298844
RGD:1624291
RGD:734870
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:68680
RGD:1624291
RGD:69372
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 JBrowse link 1 184,060,521 184,106,604 RGD:1624291
G Fgf23 fibroblast growth factor 23 JBrowse link 4 159,622,404 159,630,082 RGD:1598934
G Gc GC, vitamin D binding protein JBrowse link 14 20,267,023 20,302,577 RGD:1624291
RGD:1600115
calcitriol biosynthetic process from calciol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:1600115
RGD:13792537
RGD:1624291
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
RGD:13792537
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 JBrowse link 1 184,060,521 184,106,604 RGD:1624291
G LOC100909462 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like RGD:13792537
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
vitamin D catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 JBrowse link 3 168,097,484 168,111,920 RGD:625496
RGD:13792537
RGD:14995311
RGD:14995316
RGD:1624291
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:69373
RGD:13792537
RGD:1624291
G Fgf23 fibroblast growth factor 23 JBrowse link 4 159,622,404 159,630,082 RGD:1624291
G LOC100909462 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like RGD:13792537
vitamin D3 metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
RGD:1600115
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      organic substance metabolic process 11359
        organic hydroxy compound metabolic process 529
          vitamin D metabolic process 18
            vitamin D biosynthetic process + 12
            vitamin D catabolic process + 4
            vitamin D2 metabolic process 0
            vitamin D3 metabolic process + 6
            vitamin D4 metabolic process 0
            vitamin D5 metabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      small molecule metabolic process 1834
        vitamin metabolic process 81
          fat-soluble vitamin metabolic process 39
            vitamin D metabolic process 18
              vitamin D biosynthetic process + 12
              vitamin D catabolic process + 4
              vitamin D2 metabolic process 0
              vitamin D3 metabolic process + 6
              vitamin D4 metabolic process 0
              vitamin D5 metabolic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.