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ONTOLOGY REPORT - ANNOTATIONS


Term:fat-soluble vitamin biosynthetic process
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Accession:GO:0042362 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
Synonyms:exact_synonym: fat-soluble vitamin anabolism;   fat-soluble vitamin biosynthesis;   fat-soluble vitamin formation;   fat-soluble vitamin synthesis


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 ISO (PMID:15465040) UniProt PMID:15465040 NCBI chr2B:106,042,235...106,076,840
Ensembl chr2B:224,637,238...224,671,474
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 ISO (PMID:15795327), (PMID:16549446), (PMID:17023519), (PMID:22862690), (PMID:9415400)
(MGI:MGI:3590419|PMID:15972816)
UniProt PMID:9415400, PMID:15795327, PMID:15972816, PMID:16549446, PMID:17023519, PMID:22862690 MGI:MGI:3590419 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822
JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 ISO (PMID:15465040), (PMID:18511070) UniProt PMID:15465040, PMID:18511070 NCBI chr11:14,960,651...14,989,083
Ensembl chr11:14,656,939...14,671,584
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chr 1:95,139,171...95,151,054
Ensembl chr 1:93,876,245...93,883,528
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chr 4:94,925,048...95,040,849
Ensembl chr 4:105,589,062...105,704,098
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 ISO (PMID:19502595) BHF-UCL PMID:19502595 NCBI chr20:46,321,075...46,328,865
Ensembl chr20:47,384,818...47,390,733
JBrowse link
G SNAI2 snail family transcriptional repressor 2 ISO (PMID:18485278), (PMID:19502595) BHF-UCL PMID:18485278, PMID:19502595 NCBI chr 8:45,341,857...45,345,544
Ensembl chr 8:42,723,971...42,730,904
JBrowse link
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO (PMID:9282826) BHF-UCL PMID:9282826 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IL1B interleukin 1 beta ISO (PMID:16720713), (PMID:17023519) BHF-UCL PMID:16720713, PMID:17023519 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G TNF tumor necrosis factor ISO (PMID:1690216) BHF-UCL PMID:1690216 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO (PMID:9282826) BHF-UCL PMID:9282826 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G TNF tumor necrosis factor ISO (PMID:1690216) BHF-UCL PMID:1690216 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VDR vitamin D receptor ISO (MGI:MGI:1097206|PMID:9295274) BHF-UCL PMID:9295274 MGI:MGI:1097206 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
vitamin E biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLTP phospholipid transfer protein ISO (MGI:MGI:3622506|PMID:16467369) MGI PMID:16467369 MGI:MGI:3622506 NCBI chr20:42,237,434...42,251,189
Ensembl chr20:43,324,609...43,337,999
JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UBIAD1 UbiA prenyltransferase domain containing 1 ISO (PMID:20953171)
(PMID:23169578)
UniProtKB PMID:20953171, PMID:23169578 NCBI chr 1:10,039,415...10,161,005
Ensembl chr 1:11,260,412...11,281,381
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12524
    metabolic process 7962
      small molecule metabolic process 1311
        vitamin metabolic process 60
          fat-soluble vitamin metabolic process 32
            fat-soluble vitamin biosynthetic process 13
              vitamin A biosynthetic process 0
              vitamin D biosynthetic process + 11
              vitamin E biosynthetic process + 1
              vitamin K biosynthetic process 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.