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ONTOLOGY REPORT - ANNOTATIONS


Term:fat-soluble vitamin biosynthetic process
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Accession:GO:0042362 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
Synonyms:exact_synonym: fat-soluble vitamin anabolism;   fat-soluble vitamin biosynthesis;   fat-soluble vitamin formation;   fat-soluble vitamin synthesis


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr37:25,366,475...25,401,978
Ensembl chr37:25,366,472...25,401,509
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911
JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 IEA Ensembl GO_REF:0000107 NCBI chr21:37,553,883...37,579,744
Ensembl chr21:37,552,732...37,606,725
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 IEA Ensembl GO_REF:0000107 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor IEA Ensembl GO_REF:0000107 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr32:23,948,598...24,040,704
Ensembl chr32:23,942,954...24,040,703
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 IEA Ensembl GO_REF:0000107 NCBI chr24:36,498,343...36,503,623
Ensembl chr24:36,498,062...36,503,628
JBrowse link
G SNAI2 snail family transcriptional repressor 2 IEA Ensembl GO_REF:0000107 NCBI chr29:1,154,132...1,156,653
Ensembl chr29:1,154,036...1,156,653
JBrowse link
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma IEA Ensembl GO_REF:0000107 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G IL1B interleukin 1 beta IEA Ensembl GO_REF:0000107 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
JBrowse link
G TNF tumor necrosis factor IEA Ensembl GO_REF:0000107 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO (PMID:9282826) BHF-UCL PMID:9282826 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698
JBrowse link
G TNF tumor necrosis factor ISO (PMID:1690216) BHF-UCL PMID:1690216 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VDR vitamin D receptor IEA Ensembl GO_REF:0000107 NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470
JBrowse link
vitamin E biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLTP phospholipid transfer protein IEA Ensembl GO_REF:0000107 NCBI chr24:33,189,098...33,199,935
Ensembl chr24:33,189,099...33,199,854
JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UBIAD1 UbiA prenyltransferase domain containing 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:84,803,338...84,813,030
Ensembl chr 2:84,804,935...84,813,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    metabolic process 10637
      small molecule metabolic process 1674
        vitamin metabolic process 66
          fat-soluble vitamin metabolic process 31
            fat-soluble vitamin biosynthetic process 13
              vitamin A biosynthetic process 0
              vitamin D biosynthetic process + 11
              vitamin E biosynthetic process + 1
              vitamin K biosynthetic process 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.